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Vestn Khir Im I I Grek ; 157(4): 72-4, 1998.
Article in Russian | MEDLINE | ID: mdl-9825444

ABSTRACT

Proteolytic activity of uropepsinogen as a marker of gastroduodenal diseases of peptic character was studied in 92 children aged 7-9 years and it was analyzed in parallel with specific features of their mothers' pregnancy. The findings obtained and literature data show that the genotypical features of the fetus can play a certain role in genesis of the specific course of the mothers' pregnancy and manifest themselves phenotypically via the elevated level of uropepsinogen proteolytic activity in the children at the age of 7-9 years with possible formation of gastroduodenal diseases in them.


Subject(s)
Fetal Diseases/diagnosis , Peptic Ulcer/diagnosis , Prenatal Diagnosis , Biomarkers/urine , Child , Female , Fetal Diseases/genetics , Genetic Predisposition to Disease/congenital , Genetic Predisposition to Disease/genetics , Genetic Predisposition to Disease/urine , Genotype , Humans , Pepsinogen A/urine , Peptic Ulcer/congenital , Peptic Ulcer/genetics , Peptic Ulcer/urine , Phenotype , Pregnancy , Prenatal Diagnosis/methods , Stomach/physiopathology
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