Subject(s)
Alveolitis, Extrinsic Allergic/diagnosis , Occupational Diseases/diagnosis , Wood , Adult , Alveolitis, Extrinsic Allergic/etiology , Asthma/diagnosis , Asthma/etiology , Bronchitis/diagnosis , Bronchitis/etiology , Diagnosis, Differential , Female , Humans , Male , Occupational Diseases/etiology , Pulmonary Fibrosis/diagnosis , Pulmonary Fibrosis/etiology , UkraineSubject(s)
Air Microbiology , Air Pollutants, Occupational/adverse effects , Alveolitis, Extrinsic Allergic/etiology , Aspergillosis/etiology , Nicotiana/microbiology , Occupational Diseases/etiology , Plants, Toxic , Aspergillus fumigatus , Aspergillus nidulans , Aspergillus niger , Humans , UzbekistanABSTRACT
Clinicoroentgenological and functional manifestations of exogenic allergic alveolitis (EAA) have been studied in 143 patients. The disease is often masked and runs in the form of chronic nonspecific bronchopulmonary inflammation. The presence of antigen-dependent symptom complexes associated with involvement of other organs characterizes EAA more specifically. Finally, the disease progresses to parenchymatous interstitial fibrosis. Pulmonary ventilation and blood oxygen saturation are reduced.
Subject(s)
Allergens/immunology , Alveolitis, Extrinsic Allergic/etiology , Nicotiana/immunology , Occupational Diseases/etiology , Plants, Toxic , Pulmonary Alveoli/immunology , Adult , Alveolitis, Extrinsic Allergic/diagnosis , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Tuberculosis, Pulmonary/diagnosis , UzbekistanSubject(s)
Alveolitis, Extrinsic Allergic/immunology , Adult , Female , Humans , Middle Aged , Precipitin TestsSubject(s)
Alveolitis, Extrinsic Allergic/diagnosis , Occupational Diseases/diagnosis , Poultry , Adult , Aged , Animal Husbandry , Animals , HLA Antigens/isolation & purification , Humans , Lung/diagnostic imaging , Middle Aged , Poultry/immunology , Precipitins/isolation & purification , RadiographyABSTRACT
The experimental study made on 185 guinea pigs revealed that during the chemotherapy of destructive tuberculosis the typical bacterial forms of M. tuberculosis rapidly disappeared, but the cavities of destruction were retained and the presence of the filter-passing forms of M. tuberculosis, along with antigenemia and specific cell-mediated and humoral immunity could be detected. The use of repeated biological subculturing resulted in the reversion of the filter-passing forms of M. tuberculosis to their typical bacterial forms; simultaneously the increase of antigenemia (from subculture to subculture) and the enhancement of immune responsiveness occurred.
Subject(s)
Mycobacterium tuberculosis/isolation & purification , Animals , Antibody Formation , Antitubercular Agents/administration & dosage , Drug Therapy, Combination , Filtration , Guinea Pigs , Immunity, Cellular , Microscopy, Electron , Mycobacterium tuberculosis/immunology , Mycobacterium tuberculosis/ultrastructure , Time Factors , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Pulmonary/immunology , Tuberculosis, Pulmonary/microbiologySubject(s)
Alveolitis, Extrinsic Allergic/prevention & control , Alveolitis, Extrinsic Allergic/diagnosis , Alveolitis, Extrinsic Allergic/pathology , Animals , Chickens , Female , Humans , Mass Screening/methods , Meat-Packing Industry , Middle Aged , Occupational Diseases/diagnosis , Occupational Diseases/pathology , Occupational Diseases/prevention & control , USSRSubject(s)
B-Lymphocytes/immunology , Lung Diseases/immunology , Sarcoidosis/immunology , T-Lymphocytes/immunology , Antibodies, Bacterial/analysis , Antibody Formation , Antigens, Bacterial/analysis , Female , Humans , Immunity, Cellular , Lung Diseases/etiology , Male , Pneumonia, Pneumococcal/immunology , Sarcoidosis/etiology , Staphylococcus/immunology , Streptococcus/immunology , Tuberculosis, Pulmonary/immunologySubject(s)
Bone Diseases/diagnosis , Joint Diseases/diagnosis , Osteomyelitis/diagnosis , Tuberculosis, Osteoarticular/diagnosis , Antibodies, Bacterial/analysis , Diagnosis, Differential , Humans , Mycobacterium tuberculosis/immunology , Serologic Tests/methods , Staphylococcal Infections/diagnosis , Staphylococcus aureus/immunology , Streptococcal Infections/diagnosis , Streptococcus/immunologySubject(s)
Immunotherapy , Lymphocytes/immunology , Tuberculosis/therapy , Animals , Mice , Mice, Inbred CBAABSTRACT
Investigations carried out on CBA mice demonstrated that adult mice to which mycobacteria BCG were injected intravenously 12 months after thymectomy (in a dose of 2 mg for a period of 2 1/2 months) died of disseminated BCG infection against the background of depression of hypersensitivity of delayed type. The usual vaccine process developed in the sham-operated animals.
Subject(s)
BCG Vaccine , Thymectomy , Tuberculosis/immunology , Animals , Mice , Mice, Inbred CBAABSTRACT
Thymectomy performed in adult animals 6 months and more before the inoculation of mycobacteria H37Rv reduced the resistance to tuberculosis infection considerably. This reduction was the greater, the more time passed after the operation. There also developed immunity disturbances mainly connected with the damage of the thymus-dependent cells (depletion of thymus-dependent zones, reduction of tuberculin sensitivity of the skin and of the cytotoxic effect of lymphocytes on antigen-containing target cells).
