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2.
Acta Oncol ; 39(3): 423-8, 2000.
Article in English | MEDLINE | ID: mdl-10987241

ABSTRACT

In a series of 161 consecutive breast cancer operations, intradermal injection of Patent Blue was used to localize the sentinel node (SN). The surgical localization rate was 60%. Including the blue lymph nodes found by the pathologist, localization rate was 70%. After the first 103 operations, the surgical procedure was changed, resulting in a localization rate of 83%. Ten surgeons participated, but only one had previous experience with SN dissection. The others experienced a steep learning curve. Metastasis was found in 42 of 97 SNs (43%). In 15 cases (36%) metastasis was recognized only after step-sectioning and immunohistochemical staining for cytokeratin. In one case a benign epithelial inclusion was found. The sentinel node was false negative in 9.1% of cases. The consensus from the literature is that the best results are achieved using a combination of dye and isotopic techniques.


Subject(s)
Breast Neoplasms/pathology , Coloring Agents , Lymph Nodes/pathology , Adult , Aged , Aged, 80 and over , Axilla , Biopsy , False Negative Reactions , Female , Humans , Immunohistochemistry , Injections, Intradermal , Keratins/analysis , Lymphatic Metastasis , Middle Aged , Predictive Value of Tests , Professional Competence
3.
Acta Obstet Gynecol Scand ; 67(4): 363-5, 1988.
Article in English | MEDLINE | ID: mdl-3051884

ABSTRACT

A case is reported of a 25-year-old woman stricken with prolonged and life-threatening menorrhagia from abnormal uterine vessels resembling hemangioma cavernosum. The condition was suspected at ultrasonic investigation. Hysterectomy was performed as an emergency operation.


Subject(s)
Hemangioma/complications , Menorrhagia/etiology , Uterine Neoplasms/complications , Uterus/blood supply , Adult , Female , Hemangioma/diagnosis , Humans , Hysterectomy , Ultrasonography , Uterine Neoplasms/diagnosis
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