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Nutr Metab Cardiovasc Dis ; 27(12): 1130-1135, 2017 Dec.
Article in English | MEDLINE | ID: mdl-29170061

ABSTRACT

BACKGROUND AND AIMS: Early diagnosis of arteriosclerosis is fundamental for the prevention of cardiovascular morbidity and mortality. The current study was performed to identify major predictors of arteriosclerosis and to assess the association between arterial stiffness as measured by cardio-ankle vascular index (CAVI) and muscle mass deficit (MMD) estimated by bioelectrical impedance analysis (BIA) in middle-aged men. METHODS AND RESULTS: Data were gathered from 3356 middle-aged men who visited a health promotion center. CAVI was measured as an index of arterial stiffness. Body composition analysis was performed using BIA. MMD was positively associated with CAVI in the regression model. The odds ratios for high-CAVI (≥9.0) rose with MMD grade in a dose-dependent manner after adjusting for age, lifestyle factors and current medication use. The estimated mean CAVI rose as MMD grade increased (P for trend >0.001). CONCLUSIONS: MMD estimated from BIA was positively associated with arterial stiffness in middle-aged men. These findings show a close interaction between low muscle mass and cardiovascular risk.


Subject(s)
Arteriosclerosis/physiopathology , Body Composition , Muscle, Skeletal/pathology , Sarcopenia/pathology , Vascular Stiffness , Adult , Age Factors , Arteriosclerosis/diagnosis , Arteriosclerosis/epidemiology , Chi-Square Distribution , Cross-Sectional Studies , Electric Impedance , Humans , Linear Models , Logistic Models , Male , Middle Aged , Multivariate Analysis , Odds Ratio , Predictive Value of Tests , Pulse Wave Analysis , Republic of Korea/epidemiology , Risk Assessment , Risk Factors , Sarcopenia/epidemiology , Sex Factors
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