ABSTRACT
Trichotillomania (TTM) is an obsessive-compulsive disorder in which affected individuals recurrently pull-out hair from any region of the body, causing hair loss or alopecia. The management of TTM is a therapeutic challenge for dermatologists and consists of a combination of pharmacological and non-pharmacological alternatives. Cognitive-behavioral therapy has successfully been used to treat TTM. However, not all patients are willing to follow this treatment strategy. Unconventional support tools are proposed, such as electronic devices, internet therapies and microneedling. N-acetylcysteine and memantine are considered suitable first-line therapies thanks to their favorable safety and efficacy profile, low risk of adverse effects, and significant benefits. The use of other drugs, including fluoxetine, clomipramine, olanzapine, and naltrexone has limited evidence of variable efficacy. The present review illustrates the current treatment modalities for the management of TTM.
Subject(s)
Exanthema , Hypericum , Exanthema/chemically induced , Exanthema/diagnosis , Humans , Plant Extracts/adverse effectsABSTRACT
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Subject(s)
Humans , Male , Aged , Pemphigoid, Bullous/chemically induced , Linagliptin/adverse effects , Diabetes Mellitus, Type 2/drug therapy , Hypoglycemic Agents/adverse effects , Erythema/diagnosis , Fluorescent Antibody Technique, Indirect/methods , Adrenal Cortex Hormones/therapeutic useABSTRACT
El uso de los láseres de colorante pulsado (pulse dye laser [PDL]) y de dióxido de carbono (CO2) para el tratamiento de los dermatofibromas (DF) ha demostrado tener buenos resultados clínicos. Un total de 23 DF fueron tratados en dos sesiones con el láser de alejandrita Q-Switched de 755 nm (7,5 J/cm2, 3 mm, 50 ms), dejando entre cada sesión un intervalo de 4semanas. Para el eritema residual se utilizó el láser V Beam PDL con una longitud de onda de 595nm (10-11 J/cm2, 7 mm, 1,5 ms). En 9 de las pacientes se observó una atenuación parcial de la coloración marrón y en 14 de ellas una desaparición completa de la misma. Las pacientes refirieron un grado elevado de satisfacción después de haber realizado el tratamiento. Así mismo, 15 de las pacientes notaron una disminución en el endurecimiento de los DF. En el examen dermatoscópico previo al tratamiento, en todos los DF se observó la presencia de una red de pigmento. Esta red de pigmento desapareció en todos los casos tras la aplicación del láser. La combinación del láser V Beam PDL y del láser de alejandrita Q-Switched en los DF constituye una alternativa terapéutica adecuada que, además de buenos resultados cosméticos, ha conseguido un elevado grado de satisfacción por parte de los pacientes
Pulsed dye and carbon dioxide lasers have been applied in dermatofibroma with clinical improvement. We treated 23 dermatofibromas two times at a 4-week interval with Q-Switched alexandrite laser 755 nm (7.5 J/cm2, 3 mm, 50 ms). V Beam pulsed dye laser with a wavelength of 595nm was used for the residual erythema (10-11 J/cm2, 7 mm, 1.5 ms). A partial attenuation of brown colour was observed in 9 patients and complete disappearance of brown colour in 14 patients. Patient satisfaction was very high. Fifteen patients felt a decrease in hardening of dermatofibroma after treatment. A pigment network in dermoscopy was observed in all patients before treatment and no one after treatment. A combined treatment using both V Beam pulsed dye laser and Q-Switched alexandrite laser may be a therapeutic option to reduce the aesthetic effect of dermatofibroma with a high patient satisfaction and good cosmetic outcomes
Subject(s)
Humans , Female , Adult , Middle Aged , Histiocytoma, Benign Fibrous/therapy , Lasers, Dye/therapeutic use , Intense Pulsed Light Therapy , Dermoscopy/methods , Lasers, Solid-State/therapeutic use , Prospective Studies , Patient Satisfaction , Hypopigmentation/diagnosisABSTRACT
Pulsed dye and carbon dioxide lasers have been applied in dermatofibroma with clinical improvement. We treated 23 dermatofibromas two times at a 4-week interval with Q-Switched alexandrite laser 755nm (7.5J/cm2, 3mm, 50ms). V Beam pulsed dye laser with a wavelength of 595nm was used for the residual erythema (10-11J/cm2, 7mm, 1.5ms). A partial attenuation of brown colour was observed in 9 patients and complete disappearance of brown colour in 14 patients. Patient satisfaction was very high. Fifteen patients felt a decrease in hardening of dermatofibroma after treatment. A pigment network in dermoscopy was observed in all patients before treatment and no one after treatment. A combined treatment using both V Beam pulsed dye laser and Q-Switched alexandrite laser may be a therapeutic option to reduce the aesthetic effect of dermatofibroma with a high patient satisfaction and good cosmetic outcomes.
Subject(s)
Histiocytoma, Benign Fibrous , Laser Therapy , Lasers, Dye , Lasers, Solid-State , Histiocytoma, Benign Fibrous/radiotherapy , Humans , Lasers, Dye/therapeutic use , Lasers, Solid-State/therapeutic use , Prospective StudiesABSTRACT
No disponible
Subject(s)
Humans , Female , Child , Cardiomyopathy, Dilated/complications , Cardiomyopathy, Dilated/diagnosis , Epidermolysis Bullosa Dystrophica/complications , Epidermolysis Bullosa Dystrophica/therapy , Gastrostomy/methods , Anemia/complications , Anemia/therapy , Iron/therapeutic use , Cardiomegaly/complications , Cardiomegaly/diagnostic imaging , Electrocardiography , Pulmonary Edema/complications , Oxygen/therapeutic use , Respiration, Artificial/methods , Palliative CareABSTRACT
No disponible
Subject(s)
Humans , Female , Child , Behcet Syndrome/diagnosis , Behcet Syndrome/drug therapy , Exanthema/diagnosis , Erythema/diagnosis , Prednisone/administration & dosage , Colchicine/administration & dosage , Arthralgia/complications , Thigh/pathology , Edema/pathology , Fluorescent Antibody Technique, Direct , Diagnosis, DifferentialABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Lichen Planus/diagnosis , Lichen Planus/drug therapy , Adrenal Cortex Hormones/administration & dosage , Skin Diseases/diagnosis , Vitiligo/complications , Lichen Planus/pathology , Administration, Topical , ImmunohistochemistryABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Lip/blood supply , Vascular Diseases/diagnosis , Biopsy , Lip/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Skin Ulcer/drug therapy , Administration, Topical , Chronic Pain/complications , Analgesics/therapeutic use , Anesthesia, General , Chronic Pain/drug therapyABSTRACT
No disponible