ABSTRACT
Calcinosis cutis, a rare disorder caused by an abnormal deposit of calcium phosphate into the skin, is observed in a variety of disorders. Peculiar conditions feature skin calcifications in children and may have an iatrogenic origin. The unusual case of a baby showing periodic transepidermal elimination of calcified nodules from her fingertips is reported. In this case, fingertip calcinosis cutis was probably caused by ischemic damage due to the venous obstruction that occurred during intensive care in the neonatal period.
Subject(s)
Calcinosis/diagnosis , Infant, Premature, Diseases/diagnosis , Skin Diseases/diagnosis , Calcium Gluconate/administration & dosage , Female , Fingers/diagnostic imaging , Fingers/pathology , Humans , Iatrogenic Disease , Infant, Newborn , Infant, Premature, Diseases/drug therapy , Infant, Very Low Birth Weight , Radiography , Remission, Spontaneous , TwinsSubject(s)
Calcinosis/diagnosis , Heel , Skin Diseases/diagnosis , Calcinosis/etiology , Female , Humans , Infant , Remission, Spontaneous , Skin Diseases/etiologyABSTRACT
A child affected by giant recurrent aphthous ulcers was treated successfully over the long term with thalidomide, with no adverse reactions or reduction of therapeutic efficacy. The use of thalidomide in children for serious aphthosis is proposed.
Subject(s)
Stomatitis, Aphthous/drug therapy , Thalidomide/therapeutic use , Child , Humans , Recurrence , Thalidomide/administration & dosageABSTRACT
Papular xanthoma is a normolipemic xanthomatosis that mainly affects adults. We describe the clinical, histologic, ultrastructural, and immunologic findings in 10 children with this disease. Papular xanthoma in children has the same clinical and histopathologic features as in adults, but it appears to be self-healing within 1 to 5 years.
