Subject(s)
Hypertension/drug therapy , Renal Dialysis/adverse effects , Aged , Antihypertensive Agents/administration & dosage , Antihypertensive Agents/pharmacology , Antihypertensive Agents/therapeutic use , Cardiac Output/physiology , Drug Therapy, Combination , Female , Humans , Hypertension/etiology , Hypertension/physiopathology , Minoxidil/administration & dosage , Minoxidil/pharmacology , Minoxidil/therapeutic useABSTRACT
Low back pain with sciatica is one of the most common complaints of patients presenting to the ED, and it is usually managed on an outpatient basis. However, acute lower back pain not always derives from a benign cause. We report here the case of a 63-year-old diabetic man who presented to the ED complaining of acute low back pain with sciatica and fever. The cause was a large paravertebral abscess by Streptococcus milleri, and this was the first presenting sign of an unknown underlying colonic cancer.
Subject(s)
Abscess/microbiology , Adenocarcinoma/complications , Colonic Neoplasms/complications , Low Back Pain/etiology , Spinal Diseases/microbiology , Acute Disease , Adenocarcinoma/diagnosis , Adenocarcinoma/therapy , Colonic Neoplasms/diagnosis , Colonic Neoplasms/therapy , Humans , Male , Middle Aged , Streptococcal Infections/microbiology , Streptococcus milleri GroupSubject(s)
Amiodarone/adverse effects , Chemical and Drug Induced Liver Injury/etiology , Aged , Amiodarone/administration & dosage , Anti-Arrhythmia Agents/administration & dosage , Electrocardiography , Fatal Outcome , Female , Humans , Infusions, Intravenous , Injections, Intravenous , Transaminases/bloodSubject(s)
Cardiac Tamponade/etiology , Lymphatic Metastasis , Adenocarcinoma/complications , Adenocarcinoma/secondary , Carcinoma, Non-Small-Cell Lung/complications , Carcinoma, Non-Small-Cell Lung/diagnosis , Carcinoma, Non-Small-Cell Lung/secondary , Cardiac Tamponade/diagnosis , Fatal Outcome , Humans , Lung Neoplasms/complications , Lung Neoplasms/diagnosis , Male , Middle Aged , Pericardial Effusion/diagnosis , Pericardial Effusion/etiology , Urinary Bladder Neoplasms/complications , Urinary Bladder Neoplasms/pathologySubject(s)
Adenocarcinoma/complications , Colorectal Neoplasms/complications , Liver Abscess, Pyogenic/etiology , Staphylococcal Infections/etiology , Staphylococcus haemolyticus , Adenocarcinoma/pathology , Aged , Colorectal Neoplasms/pathology , Humans , Liver Abscess, Pyogenic/diagnosis , Liver Abscess, Pyogenic/therapy , Male , Staphylococcal Infections/diagnosis , Staphylococcal Infections/therapyABSTRACT
Hamartoma of the spleen, first described by Rokitansky in 1861 under the name of "splenoma", is a rare benign lesion that is nearly always asymptomatic. Apart from the congenital forms there are also acquired forms of splenoma that are frequently associated with hematological diseases or solid tumors. We describe the case of a man suffering from splenoma who had a spontaneous rupture of the spleen with serious hemoperitoneum a few hours after the start of polychemotherapy for squamous cell lung cancer. The close temporal relationship with the event led us to suspect that the drugs used (cisplatin, vinorelbine and corticosteroids) could have played a causal role. From a review of the literature this seems to be the third case reported of spontaneous rupture of the spleen with hamartoma, and the first with the concomitant occurrence of lung cancer.
