ABSTRACT
Aim: Radial artery occlusion (RAO) is a major complication of catheterization via transradial access (TRA). Our aim is to reveal the ability of high-sensitive C-reactive protein (hs-CRP) and complete blood count (CBC) components, which are inflammation markers, to predict RAO. Methods: Patients were divided into two groups: 103 with RAO and 300 without RAO. The relationship between CRP, CBC components and RAO was evaluated. Results: A significant increase in hs-CRP, monocyte, platelet (PLT), platelet distribution width (PDW) and plateletcrit values was observed after TRA, and only the increase in PDW, PLT and hs-CRP was found to be independent determinants in regression analysis. Conclusion: High PDW and PLT and increased hs-CRP levels are new independent determinants of the development of RAO.
The role of inflammation markers in occurrence of radial artery occlusion that restricts the transradial cardiac catheterization.
Subject(s)
Arterial Occlusive Diseases , Biomarkers , C-Reactive Protein , Inflammation , Radial Artery , Humans , C-Reactive Protein/metabolism , C-Reactive Protein/analysis , Male , Female , Biomarkers/blood , Middle Aged , Inflammation/blood , Aged , Arterial Occlusive Diseases/blood , Arterial Occlusive Diseases/etiology , Arterial Occlusive Diseases/diagnosisABSTRACT
In the present study, we aimed to investigate whether copeptin values on admission are related to left ventricle (LV) systolic function and its improvement at 6 months in ST-segment elevation myocardial infarction (STEMI) patients.In this single-center, prospective observational study, we included 122 STEMI patients from January 2016 to November 2016. LV systolic functions in the form of global longitudinal strain (GLS) in addition to conventional echocardiography parameters were evaluated on admission and at 6-month. Serum copeptin levels were determined using an ultrasensitive immunofluorescence assay.The study population was divided into 2 groups according to median values of copeptin. GLS was significantly lower in patients with high copeptin levels compared to those with low copeptin levels at early stage and 6-month (-16% (16-16.5) vs -15% (15-15.5), Pâ<â.001 and -18% (18-19) vs -16% (16-16.25), Pâ<â.001, respectively). Copeptin values were negatively correlated with an early and 6-month GLS (râ=â-0.459 at early stage and râ=â-0.662 at 6-month). In addition, we observed that copeptin values were negatively correlated with the improvement of GLS at 6-month follow-up (râ=â-0.458, Pâ<â.001 and râ=â-0.357, Pâ=â.005, respectively).Serum copeptin levels in STEMI patients at the time of admission may predict early and 6-month LV systolic function assessed by two-dimensional GLS. To the best of our knowledge, this study is the first to specifically address the relationship between copeptin values and GLS in STEMI patients.
