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2.
Obes Rev ; 11(12): 895-8, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20202134

ABSTRACT

Although in several EU Member States many public interventions have been running for the prevention and/or management of obesity and other nutrition-related health conditions, few have yet been formally evaluated. The multidisciplinary team of the EATWELL project will gather benchmark data on healthy eating interventions in EU Member States and review existing information on the effectiveness of interventions using a three-stage procedure (i) Assessment of the intervention's impact on consumer attitudes, consumer behaviour and diets; (ii) The impact of the change in diets on obesity and health and (iii) The value attached by society to these changes, measured in life years gained, cost savings and quality-adjusted life years. Where evaluations have been inadequate, EATWELL will gather secondary data and analyse them with a multidisciplinary approach incorporating models from the psychology and economics disciplines. Particular attention will be paid to lessons that can be learned from private sector that are transferable to the healthy eating campaigns in the public sector. Through consumer surveys and workshops with other stakeholders, EATWELL will assess the acceptability of the range of potential interventions. Armed with scientific quantitative evaluations of policy interventions and their acceptability to stakeholders, EATWELL expects to recommend more appropriate interventions for Member States and the EU, providing a one-stop guide to methods and measures in interventions evaluation, and outline data collection priorities for the future.


Subject(s)
Benchmarking , Health Promotion/methods , Health Promotion/standards , Obesity/prevention & control , Outcome and Process Assessment, Health Care , Feeding Behavior , Health Care Costs , Humans , Quality-Adjusted Life Years
5.
J Clin Microbiol ; 38(5): 1988-9, 2000 May.
Article in English | MEDLINE | ID: mdl-10790136

ABSTRACT

The MB/BacT mycobacterium detection system was evaluated for its performance in the susceptibility testing of Mycobacterium tuberculosis. Eighty-three M. tuberculosis isolates were processed. Results for all isoniazid-, rifampin- and streptomycin-susceptible, isoniazid-resistant, and rifampin-resistant M. tuberculosis isolates with the MB/BacT system agreed 100% with those obtained by the agar proportion method. The agreements between the two methods for streptomycin- and ethambutol-resistant isolates were 96.4 and 90.4%, respectively. The susceptibility test results were obtained in 7 days, on average. These data demonstrate that the MB/BacT system is an accurate, nonradiometric method for rapid susceptibility testing of M. tuberculosis.


Subject(s)
Antimalarials/pharmacology , Isoniazid/pharmacology , Microbial Sensitivity Tests/methods , Mycobacterium tuberculosis/drug effects , Rifampin/pharmacology , Streptomycin/pharmacology , Drug Resistance, Microbial , Humans , Microbial Sensitivity Tests/instrumentation , Mycobacterium tuberculosis/isolation & purification
6.
Neurologia ; 11(9): 332-40, 1996 Nov.
Article in Spanish | MEDLINE | ID: mdl-9004744

ABSTRACT

The prevalence of depression in Parkinson's disease (PD) is estimated to be around 40% and generally takes the form of dysthymia. Although psychological factors probably contribute to depression, data point to a relation to structural and biochemical changes linked to PD. Thus, the onset of motor impairment is often preceded by a depressive episode, although there is no consistency between the seriousness of motor disability and depression. Furthermore, depression aggravates the memory and language impairments of PD and is thought to be a risk factor for developing dementia. Regional cerebral blood flow abnormalities in the medial frontal and cingulate cortices and low 5-HIIA concentrations in cerebro-spinal fluid suggest that degeneration of the mesocorticolimbic dopaminergic system as well as dorsal raphe changes may be implicated. Assessment of depression in PD is difficult, as none of the currently available scales were specifically designed for patients with this disease Furthermore, there is a lack of well-controlled studies showing that current antidepressants are effective in PD patients or are safe for use when the motor, cognitive and autonomic impairments of PD are present.


Subject(s)
Depressive Disorder/complications , Parkinson Disease/complications , Brain/blood supply , Brain/physiopathology , Cognition Disorders , Depressive Disorder/diagnosis , Depressive Disorder/psychology , Humans , Language Disorders , Parkinson Disease/diagnosis , Parkinson Disease/physiopathology , Psychiatric Status Rating Scales , Psychomotor Disorders , Raphe Nuclei/blood supply , Raphe Nuclei/physiopathology , Regional Blood Flow , Serotonin/cerebrospinal fluid
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