Intramuscular myxoma and fibrous dysplasia of bone--Mazabraud's syndrome. A case report.

We present a case of Mazabraud's syndrome, a rare benign disease, with multiple intramuscular myxomas of the thoracic wall associated with fibrous dysplasia of bone. CT, MR imaging and ultrasonography (US) of the thorax showed 2 well circumscribed homogeneous intramuscular tumors. A US-guided needle biopsy with a large-core needle (2.0 mm) and a fine needle (0.8 mm) showed that the tumors were intramuscular myxomas with no sign of malignancy. 99mTc bone scintigraphy showed a markedly increased uptake in the right lower skull, and multiple smaller foci. CT of the skull revealed a right-sided unilateral bone thickening of the orbit and the ethmoidal cells, and right-sided exophthalmia. This case history suggests that patients with multiple intramuscular myxomas should be preoperatively examined for osseous lesions. A postoperative follow-up should also be performed to detect other soft-tissue myxomas not as yet clinically detectable, or rare osseous complications.

[CT and magnetic resonance imaging and spectroscopy for non-invasive study of regeneration of skeletal musculature after intensive therapy]. / CT og magnetisk resonansbilleddannelse og-spektroskopi anvendt til ikkeinvasiv undersøgelse af skeletmuskulaturs regeneration efter intensiv terapi.

UNLABELLED: A 50 year old man was treated in the intensive care unit. Due to a prolonged catabolic state with a loss of 35 kg of body weight, he was practically paralyzed following 70 days of treatment. After 200 days of intensive physical training, he had recuperated remarkably. CT-scans before and after the physical training revealed 90-180% increase in the muscles examined. At the femoral level the muscle/fat ratio increased from 40% to 70%, indicating less atrophy. MR-imaging of the crural muscles showed a substantial increase in the muscle mass after training. MR-fat/water proton spectra showed a decrease in the relative fat content from 0.31 to 0.13 during training, objectively measuring the remission of the severe atrophy. CONCLUSION: CT- and MR-techniques can be used for objective, non-invasive, evaluations of muscle condition, and MR-proton spektroscopy can probably be used for following the remission of muscle atrophy during physical training.

Computed tomography of the lungs in acquired immunodeficiency syndrome. An early indicator of interstitial pneumonia.

Computed tomography of the chest was performed on 42 occasions as part of the diagnostic work-up in 26 homosexual men with, or suspected of the acquired immunodeficiency syndrome (AIDS). In 17 cases both the chest radiographs and the lung scans were abnormal, and bronchoscopy and/or lung biopsy established an etiologic diagnosis in the majority of these cases. In 9 cases CT of the lungs revealed unequivocal interstitial infiltration in the presence of a normal chest radiograph, and subsequently an etiologic agent was demonstrated in all these cases. In 9 cases, patients with symptoms indicative of pulmonary infection had both a normal chest radiograph and a normal lung scan, and in none of these cases did the clinical course or additional diagnostic procedures indicate the presence of current opportunistic lung infection. CT of the lungs seems to identify accurately those patients with severe HIV-related diseases in whom invasive diagnostic procedures such as bronchoalveolar lavage and/or lung biopsy should be done.

Risk of gallstone formation after jejunoileal bypass increases more with a 1:3 than with a 3:1 jejunoileal ratio.

The rate of gallstone formation after jejunoileal bypass and the influence on the rate of the jejunoileal ratio of the functioning segment were assessed in 265 obese patients without stones in the gallbladder. After on the average 20.1 months of observation 231 patients were adequately examined for gallstones, which had developed in 2 (4%) out of 46 unoperated patients, in 9 (9%) out of 100 with a 3:1 jejunoileal ratio, and in 17 (20%) out of 85 with a 1:3 jejunoileal ratio of the functioning segment of the bypass. This result suggests that the association of ileal dysfunction and gallstone formation depends on the length of the functioning jejunum, which, according to previous studies, may reduce bile lithogenicity by stimulating bile salt synthesis.