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1.
Animals (Basel) ; 13(21)2023 Oct 28.
Article in English | MEDLINE | ID: mdl-37958108

ABSTRACT

Weed encroachment on grasslands can negatively affect herbage allowance and animal behavior, impacting livestock production. We used low-cost GPS collars fitted to twenty-four Angus crossbred steers to evaluate the effects of different levels of weed encroachment on animal activities and spatial distribution. The experiment was established with a randomized complete block design, with three treatments and four blocks. The treatments were paddocks free of weeds (weed-free), paddocks with weeds established in alternated strips (weed-strips), and paddocks with weeds spread throughout the entire area (weed-infested). Animals in weed-infested paddocks had reduced resting time and increased grazing time, distance traveled, and rate of travel (p < 0.05) compared to animals in weed-free paddocks. The spatial distribution of the animals was consistently greater in weed-free paddocks than in weed-strips or weed-infested areas. The effects of weed encroachment on animal activities were minimized after weed senescence at the end of the growing season. Pasture weed encroachment affected cattle behavior and their spatial distribution across the pasture, potentially impacting animal welfare. Further long-term studies are encouraged to evaluate the impacts of weed encroachment on animal performance and to quantify the effects of behavioral changes on animal energy balance.

2.
Br J Radiol ; 95(1133): 20211175, 2022 May 01.
Article in English | MEDLINE | ID: mdl-35220723

ABSTRACT

OBJECTIVES: High-energy Proton Beam Therapy (PBT) commenced in England in 2018 and NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We sought expert opinion on the level of provision. METHODS: Invitations were sent to 41 colleagues working in PBT, most at one UK centre, to contribute by completing a spreadsheet. 39 responded: 23 (59%) completed the spreadsheet; 16 (41%) declined, arguing that clinical outcome data are lacking, but joined six additional site-specialist oncologists for two consensus meetings. The spreadsheet was pre-populated with incidence data from Cancer Research UK and radiotherapy use data from the National Cancer Registration and Analysis Service. 'Mechanisms of Benefit' of reduced growth impairment, reduced toxicity, dose escalation and reduced second cancer risk were examined. RESULTS: The most reliable figure for percentage of radical radiotherapy patients likely to benefit from PBT was that agreed by 95% of the 23 respondents at 4.3%, slightly larger than current provision. The median was 15% (range 4-92%) and consensus median 13%. The biggest estimated potential benefit was from reducing toxicity, median benefit to 15% (range 4-92%), followed by dose escalation median 3% (range 0 to 47%); consensus values were 12 and 3%. Reduced growth impairment and reduced second cancer risk were calculated to benefit 0.5% and 0.1%. CONCLUSIONS: The most secure estimate of percentage benefit was 4.3% but insufficient clinical outcome data exist for confident estimates. The study supports the NHS approach of using the evidence base and developing it through randomised trials, non-randomised studies and outcomes tracking. ADVANCES IN KNOWLEDGE: Less is known about the percentage of patients who may benefit from PBT than is generally acknowledged. Expert opinion varies widely. Insufficient clinical outcome data exist to provide robust estimates. Considerable further work is needed to address this, including international collaboration; much is already underway but will take time to provide mature data.


Subject(s)
Neoplasms, Second Primary , Proton Therapy , X-Ray Therapy , Humans , Neoplasms, Second Primary/radiotherapy
3.
BMC Oral Health ; 17(1): 24, 2016 Jul 20.
Article in English | MEDLINE | ID: mdl-27439519

ABSTRACT

BACKGROUND: This study aimed to evaluate whether television-based dental health promotion initiatives in General Practice waiting rooms would increase patients' knowledge of and intentions to seek dental services. METHODS: This cross-sectional survey of 2,345 patients attending 49 General Practices in Brent, northwest London, evaluated the 'Life Channel' - a series of six brief health promotion advertisements, including one dental health promotion advertisement, displayed over ten minutes on television in General Practice waiting rooms. Primary outcome measures were a self-reported gain in the knowledge to contact a National Health Service (NHS) and emergency dentist, and an intention to seek dental services, attributed to viewing the Life Channel. RESULTS: Among the 1,088 patients who did not know how to contact an NHS dentist prior to the survey, and the 1,247 patients who did not know how to contact an emergency dentist prior to the survey, 48.0 % (95 % CI 45.0-51.0 %) and 35.1 % (95 % CI 32.4-37.8 %) attributed the Life Channel to educating them how to do so, respectively. Among the 1,605 patients who did not have any intention to contact a dentist prior to the survey, 15.2 % (95 % CI 13.4-17.0 %) attributed the Life Channel to creating such an intention. We report adjusted odds ratios on sociodemographic disparities in this evaluation. CONCLUSIONS: Television-based dental health promotion may significantly increase knowledge of and intention to seek dental services in this sample in London. Television-based dental health promotion may appeal more to certain population groups. More research is needed to identify longer term outcomes of television-based health promotion.


Subject(s)
Dental Care , General Practice , Health Promotion , Intention , Patient Acceptance of Health Care , Television , Cross-Sectional Studies , Humans , London
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