ABSTRACT
To get an acceptable standard of prostheses and orthoses in Sweden, the Swedish Institute for the Handicapped is testing this group of aids. One important part of the work is to draw up test instructions. In response to a request from the Swedish Institute for the Handicapped, the Laboratory of Rehabilitation Engineering at the University Hospital of Linköping in Sweden, has suggested instructions for the technical testing of monofunctional myoelectrically controlled prosthetic inspection and control factors which are important for the function of the prosthetic hand.
Subject(s)
Artificial Limbs/standards , Hand , Amputation, Surgical/rehabilitation , Biomedical Engineering/standards , Electric Power Supplies , HumansABSTRACT
Using gel electrophoresis and autoradiography, we have shown that plamitic, stearic, oleic and arachidonic acids as well as tryptophan bind to alpha-fetoprotein derived from fetal swine serum. It is also shown that these ligands bind to albumin from both fetal and adult swine serum. The results suggest that alpha-fetoprotein in the fetus has transport functions similar to albumin in the adult.
Subject(s)
Fatty Acids, Nonesterified , Tryptophan , alpha-Fetoproteins , Animals , Arachidonic Acids , Fetus , Oleic Acids , Palmitic Acids , Protein Binding , Stearic Acids , SwineABSTRACT
Studies on the incorporation of 3H-leucine established that synthesis of alpha-fetoprotein (AFP) does occur in the neonatal pig. This synthesis probably accounts for the increase in AFP concentration from 0.46 mg/ml on the day after birth to the maximum value of 1.02 mg/ml found 5 days after birth. After the 5th day, the concentration decreases successively and AFP cannot be detected by electroimmunoassay in the sera of 8-week-old pigs. During the first 3 weeks of extrauterine life, the albumin concentration in serum increases from 3 mg/ml to approximately 30 mg/ml due mainly to increased synthesis of albumin. The concentration of AFP in the fetal pig serum decreases from 3 mg/ml at 6.5 cm crown-to-rump (CR) length to 0.8 mg/ml at 28 cm CR length, whereas the albumin concentration increases from 0.2 mg/ml at 6.5 cm CR length to 1.0 mg/ml at 28 cm CR length. The total serum protein content in the fetus is approximately 20 mg/ml irrespective of gestational age. During the first day after birth there is a marked increase in both the synthesis and the concentration of total serum proteins. The concentration rises to 70 mg/ml during the first day and then slowly declines to 65 mg/ml during the 3 weeks following birth.
