ABSTRACT
Las enfermedades dermatológicas que cursan con un patrón reticular son múltiples y variadas. Aunque dicho patrón particular de presentación morfológica muchas veces es muy distintivo, usualmente es poco discutido y estudiado en el contexto clínico. A menudo, estos patrones no se abordan como una categoría diagnóstica propia. Asimismo, las etiologías de este grupo de enfermedades son diversas, desde causas vasculares, infecciosas, tumorales, inflamatorias, metabólicas o genéticas. Además, pueden variar desde condiciones relativamente benignas hasta enfermedades graves que amenazan la vida. Este artículo tiene como objetivo discutir la enfermedad de la piel que se manifiesta con lesiones reticulares y se propone un algoritmo de diagnóstico clínico, basado en el color predominante de las lesiones y los principales hallazgos clínicos, para un abordaje práctico inicial (AU)
Reticular patterns are observed in a great variety of skin diseases. While these morphologic patterns are often highly distinctive, they are seldom discussed or studied in clinical contexts or recognized as a diagnostic category in their own right. Diseases presenting with reticulate skin lesions have multiple etiologies (tumors, infections, vascular disorders, inflammatory conditions, and metabolic or genetic alterations) and can range from relatively benign conditions to life-threatening ones. We review a selection of these diseases and propose a clinical diagnostic algorithm based on predominant coloring and clinical features to aid in their initial assessment (AU)
Subject(s)
Humans , Skin Diseases/complications , Skin Diseases/etiology , Algorithms , MutationABSTRACT
Reticular patterns are observed in a great variety of skin diseases. While these morphologic patterns are often highly distinctive, they are seldom discussed or studied in clinical contexts or recognized as a diagnostic category in their own right. Diseases presenting with reticulate skin lesions have multiple etiologies (tumors, infections, vascular disorders, inflammatory conditions, and metabolic or genetic alterations) and can range from relatively benign conditions to life-threatening ones. We review a selection of these diseases and propose a clinical diagnostic algorithm based on predominant coloring and clinical features to aid in their initial assessment (AU)
Las enfermedades dermatológicas que cursan con un patrón reticular son múltiples y variadas. Aunque dicho patrón particular de presentación morfológica muchas veces es muy distintivo, usualmente es poco discutido y estudiado en el contexto clínico. A menudo, estos patrones no se abordan como una categoría diagnóstica propia. Asimismo, las etiologías de este grupo de enfermedades son diversas, desde causas vasculares, infecciosas, tumorales, inflamatorias, metabólicas o genéticas. Además, pueden variar desde condiciones relativamente benignas hasta enfermedades graves que amenazan la vida. Este artículo tiene como objetivo discutir la enfermedad de la piel que se manifiesta con lesiones reticulares y se propone un algoritmo de diagnóstico clínico, basado en el color predominante de las lesiones y los principales hallazgos clínicos, para un abordaje práctico inicial (AU)
Subject(s)
Humans , Skin Diseases/complications , Skin Diseases/etiology , Algorithms , MutationABSTRACT
Reticular patterns are observed in a great variety of skin diseases. While these morphologic patterns are often highly distinctive, they are seldom discussed or studied in clinical contexts or recognized as a diagnostic category in their own right. Diseases presenting with reticulate skin lesions have multiple etiologies (tumors, infections, vascular disorders, inflammatory conditions, and metabolic or genetic alterations) and can range from relatively benign conditions to life-threatening ones. We review a selection of these diseases and propose a clinical diagnostic algorithm based on predominant coloring and clinical features to aid in their initial assessment.
Subject(s)
Skin Diseases , Humans , Skin Diseases/diagnosis , Skin Diseases/etiology , Mutation , AlgorithmsABSTRACT
Reticular patterns are observed in a great variety of skin diseases. While these morphologic patterns are often highly distinctive, they are seldom discussed or studied in clinical contexts or recognized as a diagnostic category in their own right. Diseases presenting with reticulate skin lesions have multiple etiologies (tumors, infections, vascular disorders, inflammatory conditions, and metabolic or genetic alterations) and can range from relatively benign conditions to life-threatening ones. We review a selection of these diseases and propose a clinical diagnostic algorithm based on predominant coloring and clinical features to aid in their initial assessment.
Subject(s)
Skin Diseases , Humans , Skin Diseases/diagnosis , Skin Diseases/etiology , Algorithms , MutationABSTRACT
AIM: In a randomized double-blind study the therapeutic effect of a novel zinc-aluminium ointment was compared with placebo in patients with faecal incontinence. METHOD: A randomized double-blind trial was performed. Patients who met the inclusion criteria were randomized to receive the ointment or a placebo. All were evaluated prior to and 3 weeks after ointment application, using the Wexner incontinence score and the Fecal Incontinence Quality of Life (FIQL) score. RESULTS: Fifty patients were randomized and six were lost to follow-up, leaving 24 in the treatment and 20 in the placebo group. The average ages were 61.3 and 60.7 years. The respective Wexner scores prior to intervention were 16.6 and 16.7. They decreased significantly after treatment to 8.5 and 13.1 (P<0.001 and P=0.002 respectively). There was a significant difference in the final scores, favouring the treatment group (P=0.001). The FIQL scores for the treatment group were also significantly better in all parameters compared with those of the placebo group. CONCLUSION: The study shows that the zinc-aluminium based ointment decreases faecal incontinence significantly compared with placebo.
Subject(s)
Aluminum/therapeutic use , Fecal Incontinence/drug therapy , Ointments/therapeutic use , Trace Elements/therapeutic use , Zinc/therapeutic use , Administration, Topical , Aged , Aluminum/administration & dosage , Chi-Square Distribution , Double-Blind Method , Drug Combinations , Fecal Incontinence/psychology , Female , Humans , Middle Aged , Ointments/administration & dosage , Quality of Life/psychology , Severity of Illness Index , Trace Elements/administration & dosage , Zinc/administration & dosageABSTRACT
Introducción. La luz UVB de banda angosta (nb-UVB) ha surgido como nueva propuesta para el tratamiento del prurigo nodular. Objetivo: Describir nuestra experiencia en el uso de nb-UVB para el prurigo nodular de difícil manejo. Método: Análisis retrospectivo de cinco pacientes con prurigo nodular tratados con luz nb-UVB asociado a terapia estándar. Resultados: Se obtuvo respuesta favorable en los cinco pacientes, utilizando 23,4 mas 5,6 sesiones con una dosis acumulada de 44,5 J/cm2. El promedio de remisión fue de 4,2 mas 1,6 meses. Conclusión: La terapia nb-UVB parece constituir una alternativa eficaz para el tratamiento del prurigo nodular.
Introduction. Narrow band ultraviolet B (nb-UVB) has emerged as a new proposal for treatment of nodular prurigo. Objective. To describe our experience with nb-UVB in recalcitrant nodular prurigo. Method. Retrospective analysis of five patients treated with nb-UVB associated to standard therapy Results: We obtained a favorable response in all patients with 23.4 mas: 56 sessions, using a mean accumulative dose of 44.5 J/cm2. The mean duration of remission was 42 mas: 1.6 months. Conclusion. NS-UVB phototherapy appears to be an effective treatment for recalcitrant nodular prurigo.
Subject(s)
Humans , Male , Adolescent , Adult , Female , Middle Aged , Prurigo/radiotherapy , Ultraviolet Therapy/methods , Radiation Dosage , Phototherapy , Prurigo/pathology , Retrospective Studies , Treatment Outcome , Ultraviolet RaysABSTRACT
Se realizó un estudio del comportamiento de la resistencia nasal total y uninasal en reposo para inspiración y espiración en dos grupos de edad, utilizando un rinomanómetro equipado con máscara para las mediciones y el modelo matemático de Broms para el análisis de las curvas de presión y flujo. Se evaluó un total de 46 personas, sanos desde el punto de vista nasal, divididas en dos grupos según edad, cada uno con igual proporción de hombres y mujeres. El grupo I estuvo formado por 22 personas entre 20 y 50 años y el grupo II por 24 personas entre 51 y 80 años. Para los resultados obtenidos se calcularon medidas estadísticamente significativas al confrontar las medias de resistencia nasal total y uninasal. Al comparar por género dentro de cada grupo, sólo en el grupo I se encontró diferencias estadísticamente significativas para la varianza y el promedio
