[Bactericidal effect of lysozyme].

Isolation of lysozyme from hemolymph of Alveonasus lahorensis (Acari: Parasitiformes, Argasidae) and Hyalomma marginatum (Acari: Parasitiformes, Ixodidae) with using ultrasound is described. It was shown that the bactericidal effect of the ultrasound-extracted lysozyme against Staphylococcus aureus and Micrococcus luteus significantly exceeded that of the chicken egg lysozyme and lysozyme from ticks without ultrasound exposure. Disintegration of the hemolymph cells increased lysozyme production.

[Laparoscopic intraabdominal hernioplasty as the operation of choice in the inguinal hernia treatment].

Comparative analysis of a pain syndrome severity was done, using a visual analogous scale (VAS), basing on the analysis of performance of various kinds of laparoscopic prosthesis inserting hernioplasty for inguinal hernia, using intraabdominal (intraperitoneal onlay mesh - IPOM) and preperitoneal (transabdominal preperitoneal - TAPP) with establishment of light nets. A pain severity is trustworthy lesser in the IPOM method application--5 and 17.5 points, accordingly. The operation duration, using IPOM, have had constituted (60 +/- 20) min at average and while using TAPP--(113 +/- 42) min. The stationary postoperative state duration after the IPOM procedure was a twice lesser--1.12 and 2.8 days, accordingly. Laparoscopic prosthesis inserting intraabdominal hernioplasty, according to the IPOM method, may constitute the operation of choice, performed for inguinal hernia.

[Surgical tactics in the ulcer pyloroduodenal stenosis in decompensation stage].

In the ulcer pyloroduodenal stenosis the stages of complete and noncomplete decompensation are suggested. In 73% of observations, while performing an adequate preoperative preparation it was possible to convert pyloroduodenal stenosis from the stage of complete decompensation into the stage of noncomplete decompensation, in which the performance of organpreserving operation is possible. In the patients, suffering pyloroduodenal stenosis in the stage of noncomlete decompensation, resection of 2/3 of stomach is performed.

[Quality of life in patients after restorative operations].

The analysis of the results of the surgical treatment of colon cancer, ulcerative colitis, Crohn's disease, polyposis of colon, diverticular disease of colon on the bases of quality of life scale indexes, questionnaire SF-36 was carried out. The authors have compared the quality of life of patients who underwent surgical treatment using restorative operations after removing functional parts of the colon. The quality of life indexes in 11-12 days after the operation were higher in the first group compared with the second one. Positive influence of laparascopic intervention on quality of life considerably differs from that in the second group in 3 and 6 months and in one and three years after the operation was done.

[Methods of Barrett disease diagnostics].

Chromoesophagoscopy and photodynamic diagnosis are objective methods for diagnostic Barrett disease. Those methods can give us more detailed information about morphological changes in mucosa of esophagus.

[Primary chemoprevention of colorectal cancer in patients with inflammatory bowel diseases].

The article discusses current situation with colorectal cancer and inflammatory bowel diseases--ulcerative colitis and Crohn's desease. It has presented modern strategies of prevention colorectal cancer in this pathology and own data about the efficacy chemoprevention of cancer with 5-ASA.

[Comparative immunohistochemical features of Crohn disease and ulcerative colitis].

The determination of markers of proliferation and apoptosis in cases of Crohn disease and ulcerative colitis enables to foresee the development of morphological pathological changes occurred in a colon mucosa.

[The choice of tactics in the treatment of nonspecific ulcerative colitis].

Taking into account high probability of occurrence of the colonic mucosa morphological atypia in nonspecific ulcerative colitis, the methods of trustworthy diagnosis of dysplasia determine the choice of the treatment tactics as well as the operative intervention volume. The methods of chromocolonoscopy and photodynamical diagnosis of nonspecific ulcerative colitis are presented, their role in the treatment of patients tactic and considering the operative intervention volume was determined.

[The prognostic factors of the colonic cancer occurrence in nonspecific ulcerative colitis].

The prognostic factors of the colonic cancer occurrence in nonspecific ulcerative colitis were determined. Photodynamical diagnosis of the colonic mucosa affection, immunohistochemical determination of proliferation and apoptosis markers were applied in the investigation. The statistic-probability pattern of the malignization processes dynamics was elaborated. Algorhythm of the colonic cancer and nonspecific ulcerative colitis prognostication and diagnosis was proposed.

[Selection of methods of reconstructive operations in surgical treatment of unspecific ulcerative colitis]. / Vybor metoda rekonstruktivno-vosstanovitel'noi operatsii pri khirurgicheskom lechenii nespetsificheskogo iazvennogo kolita.

Chromocolonoscopic diagnostics in recognizing of displastics lisions of mucosa is described in the article. The indications for different methods of reconstructive operations are presented.

[Gastroesophageal reflux disease as a surgical problem]. / Gastroézofageal'naia refliuksnaia bolezn' kak khirurgicheskaia problema.

Photodynamical and chromoesophagoscopic diagnostics in recognizing of Barrett disease are described in the article. The indications for surgical treatment of esophagogastric reflux disease are presented.

[Efficacy of Norgalax and Normacol in preparation for examination of the large bowel]. / Effektivnost' primeneniia preparata "Norgalaks" i "Normakol" pri podgotovke k issledovaniiam tolstoi kishki.

The article contains the results of the prospective non-controlled study of norgalax and normacol enemas in preparation to endoscopic and radiological examinations of the large bowel. The results of investigation showed high effectiveness, simple use of enemas which can be recommended for preparation to examination of and surgery on the large bowel.

Ioffe et Al. Reply:.

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