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1.
Braz J Med Biol Res ; 22(8): 967-9, 1989.
Article in English | MEDLINE | ID: mdl-2633849

ABSTRACT

The present study was undertaken to determine if the serum of a child with severe neutropenia contained antibodies against parental neutrophils. The presence of IgG antibodies to granulocytes from both parents was demonstrated using the indirect immunofluorescence technique. These data suggest an autoimmune etiology for the neutropenia of this patient.


Subject(s)
Agranulocytosis/etiology , Autoantibodies/immunology , Autoimmune Diseases/etiology , Neutropenia/etiology , Neutrophils/immunology , Blood Cell Count , Blood Transfusion , Erythrocyte Transfusion , Humans , Infant , Male , Neutropenia/therapy , Neutrophils/analysis
2.
Braz. j. med. biol. res ; 22(8): 967-9, 1989. tab
Article in English | LILACS | ID: lil-77729

ABSTRACT

The present study was undertaken to determine if the serum of a child with severe neutropenia contained antibodies against parental neutrophils. The presence of IgG antibodies to granulocytes from both parents was demonstrated using the indirect immunofluorecence technique. These data suggest an auatoimmune etiology for the neutropenia of this patient


Subject(s)
Infant , Humans , Autoantibodies/analysis , Neutrophils/immunology , Neutropenia/immunology , Autoimmune Diseases/immunology , Fluorescent Antibody Technique , Neutrophils/analysis , Neutropenia/therapy
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