ABSTRACT
The article presents a study of a two-fluid turbulence model in the Comsol Multiphysics software package for the problem of a subsonic flow around the DSMA661 and NACA 4412 airfoils with angles of attack of 0 and 13.87 degrees, respectively. In this paper, the finite element method is used for the numerical implementation of the turbulence equations. To stabilize the discretized equations, stabilization by the Galerkin least squares method was used. The results obtained are compared with the results of other RANS, LES, DES models and experimental data. It is shown that in the case of continuous flow around the DSMA661 airfoil, the results of the two-fluid model are very close to the SST results and are in good agreement with the experimental data. When flowing around the NACA 4412 airfoil, flow separation occurs and a recirculation zone appears. It is shown that in such cases the two-fluid model gives more accurate results than other turbulence models. Implementation of the Comsol Multiphysics software package showed good convergence, stability, and high accuracy of the two-fluid turbulence model.
ABSTRACT
A computer analysis of 102 history cases of pediatric neuroblastoma of different localization established certain factors significantly influencing prognosis in this disease. Such factors as treatment modality, stage, patient's age, site and histogenetic pattern of tumor corresponded to the following values of conjugacy coefficient-0.01, 0.02 and 0.05. Treatment modality is of the highest importance. It should be complex and include radiation treatment, surgery and chemotherapy. Radiation treatment (focal dose of not less than 25 Gy) should be supported by combination polychemotherapy. Indications for surgery should be based on stage.
Subject(s)
Neuroblastoma/diagnosis , Adolescent , Child , Child, Preschool , Diagnosis, Computer-Assisted , Drug Therapy, Combination , Female , Follow-Up Studies , Humans , Infant , Male , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/mortality , Neoplasm Recurrence, Local/therapy , Neoplasm Staging , Neuroblastoma/mortality , Neuroblastoma/therapy , PrognosisABSTRACT
Blood somatomedin levels were assayed biologically in 10 children with Ewing's sarcoma and osteosarcoma and 11 children with other benign tumors. The patients were of the same age. The basal level of somatomedin in malignant bone sarcoma was similar to that in controls. However, after glucose loading, the patterns of somatomedin level curve in children and adults with normal lipo-carbohydrate metabolism were different. The difference may be due either to the specific features of child's organism or a rise in the level of blood somatomedin inhibitors.
