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2.
Vestn Akad Med Nauk SSSR ; (4): 77-82, 1989.
Article in Russian | MEDLINE | ID: mdl-2728597

ABSTRACT

An optimal correlation between the development tendencies, the popular use of reliable, practically checked technical novelties, the creation and mastering of principally new types of technique and technology is of great value in the development of science and technology programme. This task is solved by logico-semantic modelling. The prospects of the stated approach are conditioned by the possibilities of automatization of the purpose-supposing approach, that during the elaboration of medical scientific and technical programmes leads to reduction of expenditures for carrying out this function, allows to raise the demands for structure and order of program realisation, removes the duplication of search operations and information transmission in the preparatory period, that finally reduces the elaboration time and increases the quality of scientific and technical programme, provides complex approach to medical information problems. The possibilities of the method of logico-semantic modelling are described on the example of structure of the branch scientific and technical programme formation, directed to elaboration of technical and program methods of the system of automatization of medico-biological measuring.


Subject(s)
Computer Simulation , Computers , Expert Systems , Software , Humans , USSR
3.
Biull Eksp Biol Med ; 98(8): 131-4, 1984 Aug.
Article in Russian | MEDLINE | ID: mdl-6565496

ABSTRACT

The importance of the platelet count and intactness for contact Hageman's factor-dependent activation of blood plasma kallikrein has been demonstrated. The degree of kallikrein activation was in agreement with the count of platelets contained by the sample. Kallikrein activation was also found to be potentiated by the membrane fraction of washed platelets and of those destroyed by freezing and thawing. The cellular contents did not produce any significant effect on the activation in question.


Subject(s)
Blood Platelets/physiology , Kallikreins/blood , Kinins/blood , Animals , Blood Platelets/ultrastructure , Cell Fractionation , Enzyme Activation , Factor XII/physiology , Kinetics , Male , Microscopy, Electron , Platelet Count , Rats , Rats, Inbred Strains
5.
Biull Eksp Biol Med ; 91(2): 226-8, 1981 Feb.
Article in Russian | MEDLINE | ID: mdl-6164416

ABSTRACT

Scanning electron microscopy was used to study red cell aggregation caused by intravascular injection of dextran (m. w. 500 000). Two types of aggregates were revealed. Type 1 was represented by aggregates of red cells with no substantial change in the form while type 2 by aggregates with the wrinkling of the surface of red cells and enlarged area of red cell surface contacts. Both types are prone to disaggregation after injection of rheopolyglucin.


Subject(s)
Erythrocyte Aggregation/pathology , Erythrocytes/ultrastructure , Animals , Cell Communication , Dextrans/pharmacology , Erythrocyte Aggregation/chemically induced , Erythrocyte Membrane/ultrastructure , Male , Microscopy, Electron, Scanning , Rats
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