Semirigid vs Flexible Ureteroscopy in the Management of Ureteral Stones - Review.

Ureteral stones are a major clinical problem in urology that require effective and safe therapeutic options. Semirigid and flexible ureteroscopy ar two well-established procedures for treating these stones. The present review provides an outline of the advantages and disadvantages of these approaches. Semirigid ureteroscopy, which uses a rigid straight instrument, provides excellent stone visualisation and successful fragmentation. It is especially useful for proximal and bigger stones, frequently resulting in high stone-free rates and reduced procedure times. Nonetheless, its stiffness can make it difficult to navigate the delicate ureteral anatomy and increase the risk of mucosal injury. On the other hand, flexible ureteroscopy employs a more adjustable flexible scope, allowing access to complicated ureteral configurations while reducing the risk of ureteral trauma. It excels at treating distal and difficult stones but has a lower efficacy with larger stones and often requires longer procedure times. The choice between semirigid and flexible ureteroscopy is determined by patient-specific factors such as stone characteristics or anatomical considerations and the surgeon's skill. A customised approach that uses the capabilities of both treatments as needed can improve stone management outcomes while reducing potential problems. The continued advancement of technology and methodological modifications is predicted to improve the field of ureteroscopic stone management.

The Management of Reno-Ureteral Lithiasis - from Emergency Presentation to Definitive Treatment.

Introduction: The aim of our study was to retrospectively evaluate the stone-free rate after the second intervention for every performed procedure (semirigid ureteroscopy, flexible ureteroscopy, semirigid plus flexible ureteroscopy and percutaneous nephrolithotomy). Materials and methods: A total of 149 patients, who came to the emergency room of "Saint John" Emergency Clinical Hospital, Bucharest, Romania, with acute renal pathology suggesting the presence of renal and/or ureteral lithiasis confirmed by imagining (x-ray, ultrasonography or computer tomography), were included in this retrospective study, which was conducted between September 2021 and September 2022. All selected patients had an indication of emergency surgical intervention that consisted of a double-J stent mounting. We analyzed the stone-free rate after the secondary intervention, which was one of the following procedures: semirigid ureteroscopy, flexible ureteroscopy, combined semirigid and flexible ureteroscopy (F-URS), and percutaneous nephrolithotomy (PCNL). Patients came back for the secondary intervention and were reevaluated using imaging techniques. Results:Endoscopic procedures were performed by 14 surgeons over a time period of two to six weeks after the initial stenting procedure. Encrusted stents were encountered in four cases and in five cases the patients were admitted with obstruction of previously inserted stents. From the total of 149 patients, 68 (45,6%) subjects underwent semirigid ureteroscopy, with a stone-free rate of 86% (59 cases), 32 (21,4%) F-URS, with a stone-free rate of 90,6% (30 cases), 41 (27,5%) combined flexible and semirigid ureteroscopy, with a stone-free rate of 90,24% (37 cases), and eight (5,3%) patients received PCNL, with a stone-free rate of 75% (six cases). Overall stone-free rate for all procedures was 90,06%. The mean operative time was 23 minutes. No major incidents or complications occurred during the procedures. Conclusion:The emergency pre-stenting before the definitive treatment of reno-ureteral lithiasis is a safe procedure. Flexible ureteroscopy was the most successful secondary intervention, with the highest rate of achieving stone-free status.

Massive upper gastrointestinal bleeding - complication of pancreatic pseudocyst.

Massive bleeding is an unusual complication of pancreatitis. Most patients have chronic pancreatic disorders associated with pancreatic pseudocyst. We present the case of a patient, aged 49 years, known with alcohol-induced chronic pancreatitis, corporeal-caudal pancreatic pseudocyst expanded in the omental bursa, admitted to the emergency room because of hematemesis and melena, the endoscopy revealing, as a source, the erosion through the posterior gastric wall by the pseudocyst. The gastrostomy and haemostasis in situ of the source and the pseudocyst-gastric anastomosis was the solution adopted, with favourable long-term evolution.

Pseudomixoma peritonei, a rare entity difficult to diagnose and treat - case report.

The authors present the case of a 56 year-old patient diagnosed with pseudomyxoma peritonei, 4 years after being subjected to a left adnexectomy for ovarian cystadenoma. The intra-parietal insemination of the mucinous cells enabled the development,at this level, of a gelatinous mass that raised problems of differential diagnosis with irreducible incisional hernia. In what regards the preoperative signs of clinical and paraclinical diagnosis we consider them obscure and nonspecific. The abdominal computed tomography revealed the presence of a massive intraperitoneal collection, but given the rarity of this pathology the initial diagnosis was made in the course of the exploratory laparotomy. Intraoperatively it became necessary to perform the omentectomy and total hysterectomy with contralateral adnexectomy and appendectomy. The histopathological examination confirmed the diagnosis. Using cisplatin associated with aggressive surgical cytoreduction this case of pseudomixoma had a good long-term evolution. The diagnosis was a challenge, and the nonspecific slow evolution of the disease led to difficult differential diagnostic.

Relationship between outdoor and indoor air quality in eight French schools.

UNLABELLED: In the frame of the French national research program PRIMEQUAL (inter-ministry program for better air quality in urban environments), measurements of outdoor and indoor pollution have been carried out in eight schools in La Rochelle (France) and its suburbs. The buildings were naturally ventilated by opening the windows, or mechanically ventilated, and showed various air permeabilities. Ozone, nitrogen oxides (NO and NO(2)), and airborne particle (particle counts within 15 size intervals ranging from 0.3 to 15 mum) concentrations were continuously monitored indoors and outdoors for two 2-week periods. The indoor humidity, temperature, CO(2) concentration (an indicator of occupancy), window openings and building permeability were also measured. The temporal profiles of indoor and outdoor concentrations show ozone and nitrogen oxides behave differently: NO and NO(2) indoor/outdoor concentration ratios (I/O) were found to vary in a range from 0.5 to 1, and from 0.88 to 1, respectively, but no correlation with building permeability was observed. On the contrary, I/O ratios of ozone vary in a range from 0 to 0.45 and seem to be strongly influenced by the building air-tightness: the more airtight the building envelope, the lower the ratio. Occupancy, through re-suspension of previously deposited particles and possible particle generation, strongly influences the indoor concentration level of airborne particles. However, this influence decreases with particle size, reflecting the way deposition velocities vary as a function of size. The influence of particle size on deposition and penetration across the building envelope is also discussed by analyzing the I/O ratios measured when the buildings were unoccupied, by comparing the indoor concentrations measured when the buildings were occupied and when they were not (O/U ratios), and by referring to previously published studies focussing on this topic. Except one case, I/O were found to vary in the range from 0.03 to 1.79. All O/U are greater than one and increase up to 100 with particle size. PRACTICAL IMPLICATIONS: Assessing children's total exposure requires the knowledge of outdoor and indoor air contaminant concentrations. The study presented here provides data on compared outdoor and indoor concentration levels in school buildings, as well as information on the parameters influencing the relationship between outdoor and indoor air quality. It may be used as a basis for estimating indoor concentrations from outdoor concentrations data, or as a first step in designing buildings sheltering children against atmospheric pollution.