ABSTRACT
OBJECTIVE: The purpose of this study was to investigate immunohistochemically the expression of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in adenoid cystic carcinoma (AdCC) and polymorphous low-grade adenocarcinoma (PLGA) in an attempt to assess the ability of these markers to distinguish AdCC from PLGA when the histological features on routine hematoxylin and eosin are equivocal. MATERIALS AND METHODS: Fourteen specimens of AdCC, 10 PLGA, and five normal minor salivary glands fixed in 10% formalin and embedded in paraffin, were retrieved from the files of our department and were retrospectively studied with the streptavidin-biotin complex method using the epithelial membrane and carcinoembryonic antibodies. RESULTS: The immunoreactivities and the expression patterns of EMA and CEA in AdCC and PLGA were similar. CONCLUSIONS: The results of this study suggest that the immunostaining of AdCC and PLGA with EMA and CEA could not offer an adjunctive aid in differential diagnosis between these two tumors.
Subject(s)
Adenocarcinoma/diagnosis , Carcinoma, Adenoid Cystic/diagnosis , Salivary Gland Neoplasms/diagnosis , Adenocarcinoma/pathology , Adult , Aged , Aged, 80 and over , Biomarkers, Tumor/analysis , Carcinoembryonic Antigen/analysis , Carcinoma, Adenoid Cystic/pathology , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Mucin-1/analysis , Retrospective Studies , Salivary Gland Diseases/diagnosis , Salivary Gland Neoplasms/pathology , Salivary Glands, MinorABSTRACT
The case of a patient with an extensive vertical laceration of the right cheek involving Stensen's duct is reported. Treatment of parotid duct injuries varies with location and type of the injury. Immediate repair of the duct can prevent troublesome and lengthy treatment at a later date, whereas ineffective primary management may lead to complications and render treatment much more difficult.
