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1.
Br J Neurosurg ; 37(5): 1223-1227, 2023 Oct.
Article in English | MEDLINE | ID: mdl-33095079

ABSTRACT

Meningiomas have a 5 year recurrence rate of 8%. Histological grade and extent of resection are the two main prognostic factors. Cystic meningiomas represent between 2 and 4% of meningiomas, and the complete resection rate in these cases is 62.7%. 5-ALA has been shown to be useful in detecting tumour remnants that could go unnoticed by the conventional microsurgical technique, thereby achieving more complete resections. We present the case of a 66-year-old patient with a frontal convexity meningioma, presenting with a cystic component and bone invasion, who was treated using 5-ALA fluorescence-guided surgery. Fluorescence emission from the tumour tissue allowed the areas of bone invasion and the cystic wall to be identified, achieving complete resection.


Subject(s)
Meningeal Neoplasms , Meningioma , Humans , Aged , Meningioma/diagnostic imaging , Meningioma/surgery , Meningioma/pathology , Aminolevulinic Acid , Meningeal Neoplasms/diagnostic imaging , Meningeal Neoplasms/surgery , Meningeal Neoplasms/pathology , Fluorescence
3.
Rev. neurol. (Ed. impr.) ; 66(4): 113-120, 16 feb., 2018. tab, graf
Article in Spanish | IBECS | ID: ibc-172119

ABSTRACT

Introducción. En nuestro entorno, el envejecimiento poblacional ha convertido el manejo del traumatismo craneoencefálico (TCE) en etapas avanzadas de la vida en un problema de frecuencia creciente.Objetivo. Valorar la asociación entre la edad y el pronóstico vital y funcional de pacientes intervenidos por TCE. Pacientes y métodos. Analizamos retrospectivamente una serie de 404 pacientes intervenidos en nuestro centro entre los años 2000 y 2015: 144 jóvenes (12-44 años), 77 adultos (45-64 años), 148 pacientes geriátricos (65-79 años) y 26 supergeriatricos (> 80 años). Revisamos las características demográficas y nosológicas de la población, y el pronóstico vital y funcional (escala pronostica de Glasgow, GOS) en el momento del alta y a los seis meses. Resultados. La edad presenta asociación lineal positiva tanto con la mortalidad intrahospitalaria como con la proporción de pacientes con pronóstico desfavorable (GOS 1-3) en el alta y a los seis meses (p < 0,001). Tomando como referencia la población de jóvenes, el riesgo relativo para pronostico desfavorable a los seis meses fue de 1,5 (IC 95%: 1,04-2,19) para los adultos, 2,37 (IC 95%: 1,77-3,17) para los geriátricos y 3,5 (IC 95%: 2,63-4,70) para los supergeriatricos. Estos últimos presentan una mortalidad durante el ingreso del 77,78% y un porcentaje de mal pronóstico funcional a los seis meses del 94,44%. Conclusión. El aumento de la edad es un factor determinante negativo mayor en el pronóstico de pacientes sometidos a craneotomía por TCE. Un conocimiento preciso de estos resultados y una adecuada discusión preoperatoria con la familia resultaran de gran ayuda en el proceso de toma de decisiones (AU)


Introduction. In our setting, the ageing of the population has led to management of traumatic brain injury (TBI) in the later stages of life becoming an increasingly frequent problem. Aim. To evaluate the association between age and the functional and survival prognosis of patients who have undergone surgery due to TBI. Patients and methods. We performed a retrospective analysis of a series of 404 patients submitted to surgery between the years 2000 and 2015: 144 youngsters (12-44 years), 77 adults (45-64 years), 148 geriatric patients (65-79 years) and 26 'super geriatric' patients (> 80 years). We reviewed the demographic and nosological characteristics of the population, the survival and functional prognosis (Glasgow Outcome Scale, GOS) on discharge and at six months. Results. Age presents a positive linear association with both intra-hospital mortality and the proportion of patients with an unfavourable prognosis (GOS 1-3) on hospital discharge and at six months (p < 0.001). Taking the population of youngsters as a reference, the relative risk for an unfavourable prognosis at six months was 1.5 (95% CI: 1.04-2.19) for adults; 2.37 (95% CI: 1.77-3.17) for the geriatric patients; and 3.5 (95% CI: 2.63-4.7) for the ‘super geriatric’ patients. These latter present a mortality rate while in hospital of 77.78% and a percentage of poor functional prognosis at six months of 94.44%. Conclusion. Increased age is a major negative determining factor in the prognosis of patients who undergo a craniotomy due to TBI. More precise knowledge of these outcomes and an adequate pre-operative discussion with the family will be an invaluable aid in the decision-making process (AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Young Adult , Adult , Middle Aged , Aged , Aged, 80 and over , Craniotomy/statistics & numerical data , Brain Injuries, Traumatic/surgery , Brain Contusion/rehabilitation , Hematoma, Epidural, Cranial/rehabilitation , Hematoma, Subdural/rehabilitation , 50293 , Treatment Outcome , Brain Injuries, Traumatic/complications , Prognosis , Retrospective Studies , Brain Injuries, Traumatic/rehabilitation , Indicators of Morbidity and Mortality
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