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J Enzyme Inhib Med Chem ; 24(5): 1128-32, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19772485

ABSTRACT

Galinsosides A (1) and B (2), new flavanone glucosides together with two known flavanones, 7,3',4'-trihydroxyflavanone (3) and 3,5,7,3',4'-pentahydroxyflavanone (4) have been isolated from an ethyl acetate- soluble fraction of Galinsoga parviflora. Their structures were assigned on the basis of spectral studies. Compound 1 showed significant antioxidant and urease inhibitory activity while compound 2 was moderately active. On the other hand, 2 showed inhibitory potential against alpha-glucosidase.


Subject(s)
Asteraceae/chemistry , Flavanones , Glucosides , Plant Extracts/chemistry , Plant Extracts/pharmacology , Antioxidants/chemistry , Antioxidants/pharmacology , Flavanones/chemistry , Flavanones/pharmacology , Glucosides/chemistry , Glucosides/pharmacology , Magnetic Resonance Spectroscopy , Molecular Structure , Plant Structures/chemistry , Urease/antagonists & inhibitors
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