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Transplant Proc ; 37(5): 2179-80, 2005 Jun.
Article in English | MEDLINE | ID: mdl-15964372

ABSTRACT

Current rescue therapies for acute steroid-resistant rejection, such as OKT3 and high-dose tacrolimus, are not uncommonly associated with side effects that contribute to significant morbidity of the patient. Basiliximab is a chimeric monoclonal antibody that acts as an interleukin-2 receptor antagonist on the surface of activated T lymphocytes. It has until now only been used as immunoprophylaxis in adult liver transplant patients. In this report, we describe the use of Basiliximab as rescue therapy in a case of acute steroid-resistant rejection in an adult living related liver transplant recipient.


Subject(s)
Antibodies, Monoclonal/therapeutic use , Graft Rejection/drug therapy , Immunosuppressive Agents/therapeutic use , Liver Transplantation/immunology , Recombinant Fusion Proteins/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Basiliximab , Female , Humans , Liver Function Tests , Middle Aged , Postoperative Period
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