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10.
Biull Eksp Biol Med ; 91(3): 338-40, 1981 Mar.
Article in Russian | MEDLINE | ID: mdl-7248511

ABSTRACT

Immunologic analysis of the antigenic spectrum of the oral mucosa of man has shown a correlation between the properties as well as distribution pattern in the body of entodermal antigen of man and animals (dogs). This formed a basis for an assumption about the existence in at least two representatives of mammals of an antigen with similar properties discovered by the authors.


Subject(s)
Antigens/analysis , Endoderm/immunology , Mouth Mucosa/immunology , Animals , Chemical Phenomena , Chemistry, Physical , Dogs , Humans , Organ Specificity , Species Specificity , Tissue Distribution
12.
Biull Eksp Biol Med ; 90(11): 569-70, 1980 Nov.
Article in Russian | MEDLINE | ID: mdl-7004525

ABSTRACT

Spontaneous stomatitis in dogs gives rise to the appearance in ectodermal derivatives of an additional antigen that is not detectable in normal oral mucosa. The immunofluorescence and immunoperoxidase methods were used to study the intracellular localization of entodermal antigen in various part of the alimentary tract. Clear and contrast localization of the test antigen in all parts of the alimentary tract warrants a conclusion that this antigen is a mucus component secreted by alimentary tract glands. No antigen under test was found in oral mucosa portions of entodermal origin except for soft palate. Entodermal antigen was not detected either in small mucus-forming glands.


Subject(s)
Antigens/analysis , Endoderm/immunology , Gastric Mucosa/immunology , Intestinal Mucosa/immunology , Mouth Mucosa/immunology , Animals , Dogs , Fluorescent Antibody Technique , Immunoenzyme Techniques , Intestine, Large/immunology , Intestine, Small/immunology , Palate/immunology , Palate, Soft/immunology , Tongue/immunology
15.
Article in Russian | MEDLINE | ID: mdl-442906

ABSTRACT

A new qualitative condition "illness" arises when its quantitative state attains a certain level (appearance of degenerative spinal changes). The qualitative verge is conventional, dynamic. The changes in the spinal defensive mechanisms shown by nervous system lesions and circulatory disorders may be regarded as its verge. Long-term remissions, appearing in a reverse transition of the qualitative verge may be considered as a clinical recovery in stabilization or even eventual progress of degenerative spinal changes. It is inadmissable to identify spinal degenerative processes with diseases produced by them. Varied and phasic clinical symptomatology appearance of long-term remissions, availability of the most informative methods of study for each phase, the effectiveness of therapeutic approaches and preventive measures, as well as the interests of differential diagnosis permit to consider the clinical manifestations of separate stages in the degenerative process as specific nozological forms regardless of their common vertebrogenic origin. The formulation of a clinical diagnosis depends to a large extent upon the generally acknowledged classification of the nervous system.


Subject(s)
Spinal Diseases/diagnosis , Humans , Intervertebral Disc Displacement/diagnosis , Osteochondritis/diagnosis , Pain , Syndrome
16.
Biull Eksp Biol Med ; 82(10): 1234-7, 1976 Oct.
Article in Russian | MEDLINE | ID: mdl-1029510

ABSTRACT

An additional component absent in the same areas of the mouth under normal conditions appeared in dogs with spontaneous stomatitis in the ectodermal derivatives (mucosa of the cheeks, tongue and the hard palate). This component proved to be fully identical to the antigens of the mucosa of the soft palate, esophagus, stomach, small and large intestine, which were entodermal derivatives. No entodermal antigen was revealed in the other organs and tissues under study.


Subject(s)
Antigens/isolation & purification , Mouth Mucosa/immunology , Stomatitis, Aphthous/immunology , Animals , Digestive System/immunology , Dogs , Endoderm , Palate/immunology , Recurrence , Tongue/immunology
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