ABSTRACT
The changes in blood coagulative properties, which occur in the treatment with medical leeches, were studied in 57 patients with coronary heart, rheumatic and chronic pulmonary diseases. Hirudin therapy was established to affect blood coagulation. The leech salina penetrated into the skin wound to block hemostasis. Having entered the circulating blood, some part of the saliva normalized its impaired coagulative properties. The correction of the above abnormalities and related bleeding indicate it beneficial to use hirudin therapy in secondary coagulopathies and circulatory decompensation.
Subject(s)
Blood Coagulation/drug effects , Cardiovascular Diseases/therapy , Hirudins/pharmacology , Coronary Disease/therapy , Hirudin Therapy , Humans , Middle Aged , Pulmonary Heart Disease/therapy , Rheumatic Heart Disease/therapyABSTRACT
The authors analyze the laboratory and instrumental data obtained before and after single administration of leeches. Demonstrate that the animal's saliva corrects the coagulation properties of the circulating blood; inhibits platelet aggregation; that it may be used for blood letting; possesses hypotensive and anti-sclerotic properties; improves myocardial supply and its contractility. Based on a large clinical material the authors provide evidence for advisability of the use of hirudotherapy in patients suffering from coronary heart disease, essential hypertension, atherosclerosis, chronic cer pulmonale, and circulatory decompensation.
Subject(s)
Cardiovascular Diseases/therapy , Leeches , Aged , Animals , Cardiovascular Diseases/blood , Evaluation Studies as Topic , Female , Humans , Lung Diseases/blood , Lung Diseases/therapy , Male , Middle Aged , Remission InductionABSTRACT
By collating the results of qualitative and quantitative analysis of the ECG with the findings of selective coronary angiography obtained from 32 patients with coronary heart disease, considerable informative value of the planimetric method of the quantitative analysis of the ECG has been proved. It is concluded that the quantitative interpretation of changes in the areas of the initial and end fragments of the ventricular complex of the ECG contributes to early diagnosis of coronary heart disease and in some cases it helps to specify the localization of coronary impairments.
