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J Natl Compr Canc Netw ; 10(7): 821-9, 2012 Jul 01.
Article in English | MEDLINE | ID: mdl-22773798

ABSTRACT

These NCCN Guidelines Insights highlight the important updates/changes specific to the management of metastatic breast cancer in the 2012 version of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer. These changes/updates include the issue of retesting of biomarkers (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2) on recurrent disease, new information regarding first-line combination endocrine therapy for metastatic disease, a new section on monitoring of patients with metastatic disease, and new information on endocrine therapy combined with an mTOR inhibitor as a subsequent therapeutic option.


Subject(s)
Antineoplastic Agents, Hormonal/therapeutic use , Breast Neoplasms/drug therapy , Breast Neoplasms/pathology , Protein Kinase Inhibitors/therapeutic use , Biomarkers, Tumor , Breast Neoplasms/metabolism , Female , Humans , Neoplasm Metastasis , TOR Serine-Threonine Kinases/antagonists & inhibitors
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