ABSTRACT
Peculiarities of the microangioarchitectonics in the trunks, intermediate and terminal villi of the placenta have been described at a noncomplicated pregnancy. Signs of neovasculogenesis are demonstrated in the microcirculatory bed of the terminal villi. Possible connection between reduction of the paravasal capillary network, as the intermediate villi become mature, and neovasculogenesis is discussed.
Subject(s)
Placenta/blood supply , Female , Histological Techniques , Humans , Microcirculation/ultrastructure , Microscopy, Electron, Scanning , Placenta/ultrastructure , PregnancyABSTRACT
Pathologic background has been evaluated for premature delivery of 38-39, 30-37 and 20-27 week fetuses. The trial involved 115 placentas in abortion and 60 control cases of normal pregnancy. A combination of modern techniques involving histological, enzymatic and chemical has been employed as well as light microscopy. The destructive, compensatory and adjustment processes observed in the placentas were correlated topographically. The parameters registered were compared to clinical and laboratory findings. The structural basis has been defined for compensatory alterations in the placenta and pathomorphological criteria have been derived for progressive functional insufficiency at various gestation periods.
Subject(s)
Abortion, Spontaneous/pathology , Placenta/pathology , Abortion, Threatened/pathology , Female , Humans , Microscopy, Electron , Obstetric Labor, Premature/pathology , Pregnancy , Pregnancy Trimester, Second , Pregnancy Trimester, ThirdABSTRACT
Gel precipitation was employed to detect antibodies to the A-polysaccharide specific antigenic determinant in blood serum of 131 patients with different versions of rheumatic fever. 21 patients with non-rheumatic myocarditis, 25 convalescents following quinsy, and 58 donors. It was established that high titers of antibodies to A-polysaccharide in patients with protracted and latent rheumatic fever correlate with the clinical and morphological signs of the process activity. Elevation of the antibody titers after mitral commissurotomy made to 107 patients was recorded only in those with exacerbation or activation of rheumatic fever. During the first year after mitral commissurotomy as well as at the preoperative period, the titers of antibodies to A-polysaccharide in patients with protracted rheumatic fever were higher than in those with latent and inactive disease patterns.