[Humoral immune response against Trichomonas tenax in patients with chronic catarrhal gingivitis before and after specific Fasigyn treatment]. / Khmoralen imunen otgovor steshtu Trichomonas tenax pri bolni s gingivitis catarrhalis chronica predi i sled spetsifichno lechenie Fasigyn.

The following parameters were studied in 71 subjects, aged from 7 to 38 with chronic catarrhal gingivitis, invaded by T. tenax: oral-hygienic index of Green and Vermillion before the specific Fasigyn treatment and on 3, 7, 14 and 30 days after the treatment; the presence of complement-combining antibodies against T. tenax and the dynamics of antibody synthesis by 3, 6, 12 and 15 month after the treatment. Thirty one subjected with chronic catarrhal gingivitis, non invaded by T tenax were studied as controls. It has been established that in 53.52% of the subjects with chronic catarrhal gingivitis, invaded by T tenax, the inflammatory changes in gingiva disappeared as early as the third day after the specific Fasigyn treatment and in the rest--by 30 day. Higher values of complement-combining antibodies against T. tenax with a titre from 1:40 to 1:2569 were established in 65.34% from the subjects with chronic catarrhal gingivitis, invaded by T. tenax. The titre of antibodies sharpy decreased by month 3 and was normalized by months 6-12 after Fasigyn treatment.

[Comparative immunoelectrophoretic studies of total water-soluble extracts of Trichomonas vaginalis, T. tenax and T. hominis]. / Vergleichende immunelektrophoretische Untersuchungen totaler wasserlöslicher Extrakte von Trichomonas vaginalis, T. tenax und T. hominis.

An antigen characterization was carried out by the method of two-dimensional immunoelectrophoresis, and on this basis the antigen community and the antigenic differences between the 3 Trichomonas species parasitic in man were investigated. In the homologous antigen-antibody-systems a maximum number of precipitation curves is formed--21 in T. vaginalis and 20 each in T. tenax and T. hominis. According to our setting of the experiment T. vaginalis has 5 specific antigens in regard to T. tenax and 3 in regard to T. hominis. T. tenax has 2 specific antigens in regard to T. vaginalis and 7 in regard to T. hominis, T. hominis has 2 specific antigens in regard to T. vaginalis and 3 in regard to T. tenax. The presence of antigenic differences is important for the immunological characterization of the 3 species and demonstrates their validity.