ABSTRACT
In order to determine trace amounts of lead in copper gluconate by atomic absorption spectrometry (AAS), the authors investigated a separation and pre-concentration procedure using a co-precipitation technique with bismuth. After ashing 2.0 g of the sample by means of a dry process, the ash was dissolved in (1â100) nitric acid and 75 µg of bismuth was added. Lead was co-precipitated by using an ammonium solution controlled to pH 9.5-10.5. The precipitate was left at room temperature for over 15 minutes to age, and then washed with a (3â100) ammonium solution three times. The precipitate was dissolved in (1â100) nitric acid and then analyzed by AAS. The quantification limit of this method was 0.5 mg/kg, and the trueness, repeatability and intermediate precision were 99.6%, 4.2% and 4.2% at the spiked concentration of 0.5 mg/kg, and 94.4%, 2.8% and 4.0% at the spiked concentration of 5.0 mg/kg, respectively. Thus, the present method for trace analysis of lead in copper gluconate was validated.
Subject(s)
Bismuth , Chemical Precipitation , Food Additives/chemistry , Food Contamination/analysis , Gluconates/chemistry , Lead/analysis , Spectrophotometry, Atomic/methods , Ammonium Compounds , Calcium Carbonate , Citrates , Drug Combinations , Hydrogen-Ion Concentration , Magnesium Oxide , TemperatureABSTRACT
A 56-year-old gastric cancer patient with multiple lung metastases and dilated cardiomyopathy was treated by chemotherapy with TS-1. This case was judged to be unresectable. TS-1 (100 mg/body/day) was orally administered for 4 weeks followed by a drug-free 2-week period as 1 course. At the completion of 3 courses, the multiple lung metastases were assessed to show a complete response (CR). There were no side effects and no hospitalization. This chemotherapy is being continued, and a CR in the lung and no change of the gastric cancer have been maintained for 15 months (10 courses).
Subject(s)
Antimetabolites, Antineoplastic/therapeutic use , Carcinoma, Signet Ring Cell/drug therapy , Lung Neoplasms/drug therapy , Lung Neoplasms/secondary , Oxonic Acid/therapeutic use , Pyridines/therapeutic use , Stomach Neoplasms/drug therapy , Tegafur/therapeutic use , Administration, Oral , Carcinoma, Signet Ring Cell/secondary , Cardiomyopathy, Dilated/complications , Drug Administration Schedule , Drug Combinations , Humans , Male , Middle Aged , Stomach Neoplasms/pathologyABSTRACT
We herein describe the case of a 48-year-old man who presented to our hospital with abdominal distension and pain. Preoperative studies including abdominal ultrasonography and computed tomography failed to determine the cause of the pain. At laparotomy, a giant cystic tumor of the small bowel mesentery was found. Histologically, the tumor was diagnosed as a cystic lymphangioma. Although mesenteric lymphangiomas are rare, especially in adults, they should be considered as a possible cause of acute abdomen.
