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Gan To Kagaku Ryoho ; 35(6): 1021-4, 2008 Jun.
Article in Japanese | MEDLINE | ID: mdl-18633238

ABSTRACT

We watched and analyzed patient cardiac functions especially with a "Phased tracking method" to detect rapid motion of the heart. The patient suffered from congestive heart failure while depending on anthracycline cumulative doses, but now has been living more than 10 years after relapsed acute myeloblastic leukemia. To avoid congestive heart failure with increasing highly tumoricidal anthracycline doses, cardiac function should be monitored closely in connection with treatment schedules and proposed accurate therapeutic index.


Subject(s)
Anthracyclines/adverse effects , Anthracyclines/therapeutic use , Cardiomyopathy, Dilated/chemically induced , Leukemia, Myeloid, Acute/drug therapy , Aged , Cardiomyopathy, Dilated/diagnostic imaging , Cardiomyopathy, Dilated/physiopathology , Female , Humans , Recurrence , Time Factors , Ultrasonography
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