[Digestive pathology and digestive function of small intestine mucous layer]. / Pishchevaritel'naia funktsiia pristenochnogo slizistogo sloia tonkoi kishki pri patologii organov pishchevareniia.

The research of small intestine mucous layer at children and adults is carried out. It is revealed high meanings enzyme distribution in human small intestine mucous layer and their change at celiac disease, food allergy, short-bowel syndrome.

[The trypsin activity in the chyme and parietal layer of the mucus in experimental exclusion of the Brunner's gland section of the duodenum in rats]. / Aktivnost' tripsina v khimuse i pristenochnom sloe slizi pri éksperimental'nom vykliuchenii brunnerovskogo otdela dvenadtsatiperstnoi kishki u krys.

The duodenal glands secretion into intestine was excluded by surgical ablation or ligation of Brunner's glands region. The trypsin activity in chyme and adherent mucous layer was reduced following these manipulations. Possible reasons for changes established are discussed.

[Optimal method of isolation of supra-epithelial mucous layer of the small intestine in experimental animals]. / Optimizatsiia metoda vydeleniia nadépitelial'nogo slizistogo sloia tonkoi kishki éksperimental'nykh zhivotnykh.

Experimental data on the activity of digestive endo- and exo-hydrolases in supra-epithelium mucus layer has been presented. Mucus layer has been obtained on special vibrating setting from the turned out intestinal preparation. Different conditions of work and medium of isolation have been used. The setting permits to obtain intestinal supra-epithelium mucus more completely and also prevents epithelium damages and hiting of damaged villi.

[The digestive function of the supraepithelial mucosal layer of the small intestine]. / O pishchevaritel'noi funktsii nadépitelial'nogo slizistogo sloia tonkoi kishki.

The results of biochemical estimation of the activity of intestinal proper and pancreatic enzymes in enteral contents, mucous layer and homogenate of small intestine's membrane suggest an important role of supraepithelial mucous layer in actualization of final stages of the food hydrolysis. The term "parietal digestion" is suggested for designation of a sum of hydrolytic processes in the layer of mucus.

[The effect of a lipid food component on enzymatic activity of rat liver endoplasmic reticulum upon the action of polychlorinated biphenyls]. / Izuchenie vliianiia lipidnogo komponenta pishchi na aktivnost' fermentov éndoplazmaticheskogo retikulum pechenia krys pri vozdelstvii polikhlorirovannykh difenilov.

The authors have studied the character of changes in the content of cytochrome P450 and b5, in the oxidation rate of amidopyrine, dimethyl-aniline and aniline, in the NADPH- and ascorbate-dependent lipid peroxidation systems, as well as in glucose-6-phosphatase and acetylesterase activities in the liver microsomes of the rats on semisynthetic diets, including 50% (according to calorific value) of butter or sunflower oil, or receiving fat-free diet (0.5% of sunflower oil) in different terms (4 and 70 days) after a single intragastric administration of a mixture of polychlorinated diphenyls, chlorinated biphenyl (500 mg/kg). It is shown that the degree and character of the microsomal enzymes studied, as well as the changes in the liver structure under the action of chlorinated biphenyl depend, to a certain extent, on the quality and quantity of fat in the diet.