ABSTRACT
A high-pressure liquid chromatographic procedure for the simultaneous determination of niacin and niacinamide in multivitamin preparations was developed and evaluated. Reversed-phase liquid chromatography with dioctyl sodium sulfosuccinate in the mobile phase is utilized for the analysis. The accuracy and precision of the procedure were compared with those of the currently official procedure.
Subject(s)
Niacinamide/analysis , Nicotinic Acids/analysis , Vitamins/administration & dosage , Chromatography, High Pressure Liquid , Drug Combinations , MethodsSubject(s)
Ampicillin/analogs & derivatives , Ampicillin/analysis , Chelating Agents , Copper , MethodsABSTRACT
An indirect complexometric method is described for the determination of piperazine alone or in its pharmaceutical preparations. The method involves treatment of the aqueous solution of piperazine with carbon disulphide, ammonia solution and a known excess of cupric acetate, filtration of the formed precipitate and determination of the excess cupric acetate with EDTA using PAR as indicator.
