[Effects of phenibut on parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome and various types of systemic hemodynamics].

Administration of phenibut (0.25 g) during 4 weeks as a means of rehabilitation promoted optimization of the biochemical status and cerebral blood circulation in swimmers with various types of systemic hemodynamics, which were examined 20 minutes after warm-up.

[Effects of aminalon, fenibut, and picamilon on the typological parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome].

The administration of aminalon (0.25 g), fenibut (0.25 g) and picamilon (0.10 g) during 4 weeks as a means of recovery for swimmers with disadaptation syndrome helped to optimize the biochemical status and cerebral circulation 20-min after warm-up. The reaction to the warm-up load under test conditions was characterized by increasing total blood filling of the brain and difficulty of venous outflow. Under the action of drugs, a decrease in blood filling of the brain and increase in venous blood outflow from the cerebral basin was observed 20 min after load in all test groups (except the hypokinetic group taking picamilon).

[Types and variants of cerebral circulation in healthy young people in clino-stasis and anti-orthostasis]. / Tipy i varianty tserebral'nogo krovoobrashcheniia u zdorovykh liudei molodogo vozrasta v klino- i anti-ortostaze.

This paper presents the results of investigations of 199 apparently healthy individuals aged 18-22 years. Analysis of the findings yielded concepts of the types of cerebral circulation--the types of cerebral microcirculation and the variants brain volumia--the variants of summarized pulse blood filling of this organ. To define the types and variants of cerebral hemodynamics makes it possible to predict the magnitude and direction of brain vasomotor responses aimed at optimizing arterial blood stream into the region and venous blood outflow under antiorthostasis. The types and variants of cerebral circulation that most and least favourable as to a risk for regional venous congestion. The views of the types and variants of cerebral circulation open up fresh opportunities for in-depth study of the most important parameters of cardiovascular performance. A typological analysis of cerebral circulation can find a wide application in clinical practice for "the passportization" of the most important physiological parameters of regional blood flow.

[Laws of typological interactions of clino- and antiorthostatic systemic and cerebral circulation in children]. / Zakonomernosti tipologicheskogo vzaimodeistvii sistemnogo i tserebral'nogo krovoobrashcheniia u detei v klino- i antiortostaze.

Based on P. K. Anokhin's systems approach, the authors analyze the typological features of the mechanisms of clinostatic and anti-orthostatic systemic and cerebral circulation in children aged 7-9 years. Children with eukinetic systemic circulation have stable total peripheral vascular resistance in antiorthostasis, the mechanisms of cerebral hemodynamic regulation ensure constriction of local arterioles, those with hypokinetic systemic circulation have decreased total peripheral vascular resistance and lower constriction of cerebral arteries and arterioles. In hyperkinetic circulation, total peripheral resistance increases with slight constriction of cerebral arterioles and marked deterioration of venous blood outflow from the cerebral pool. The typological features of systemic and cerebral circulation should be borne in mind in pediatric clinical practice. The findings allow one to mathematically predict the changes occurring in anti-orthostatic hemodynamics in the context of its typological features.