ABSTRACT
A double-blind study was performed on ninety-six parturients of the Lima Maternity Hospital, Peru, with some evidence of foetal distress who were given indistinguishably piracetam or a placebo at random in order to investigate the effects of the drug on the foetus. The conditions of the new-born babies who had received piracetam were superior to those of the babies treated with the placebo, as evaluated with the Apgar at 1, 5 and 10 minutes after birth and on the basis of the neurological and clinical examination as from 24 hours until they were released. In addition, the reduction of the duration of the labour in the patients treated with piracetam as compared with the control group was obvious.
Subject(s)
Fetal Distress/drug therapy , Obstetric Labor Complications/drug therapy , Piracetam/therapeutic use , Pyrrolidinones/therapeutic use , Amniotic Fluid/analysis , Apgar Score , Birth Weight , Clinical Trials as Topic , Female , Fetal Blood/analysis , Fetal Heart/physiology , Heart Rate , Humans , Hydrogen-Ion Concentration , Infant, Newborn , Piracetam/administration & dosage , Placenta/anatomy & histology , Pregnancy , Random Allocation , Time FactorsABSTRACT
Se hizo un estudio doble ciego en 96 parturientas de Hospital Maternidad de Lima.Peru, con evidencias de sufrimiento fetal, a quienes se les administro indistintamente piracetam o placebo por randomizacion, para estudiar los efectos de la droga sobre el feto. Las condiciones de los recien nacidos que recibieron piracetam fueron superiores a la de aquellos a los que se administro placebo, evaluados por el Apgar a 1,5 y 10 minutos del nascimiento, y por el examen neurologico y clinico, desde las 24 horas hasta que fueron dados de alta.Fue notoria, ademas, la abreviacion de la labor de parto en las pacientes que recibieron piracetam, con relacion al grupo control
