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1.
Rev Laryngol Otol Rhinol (Bord) ; 112(1): 17-9, 1991.
Article in English | MEDLINE | ID: mdl-2052781

ABSTRACT

Fifty audiologically normal young adults, 25 men and 25 women, were submitted to the auditory brainstem response (ABR) test. The mean latencies of the waves I, II, III, IV and V and the interpeak latencies (IPLs) I-III, I-V and III-V were calculated and compared to the normative values published by other groups. We have observed a great similarity among these values, specially in the interpeak latencies. The latencies of the principal ABR parameters were compared between the sexes showing significant differences in all the waves, particularly in the wave V. No significant correlations were found among the values when the head size and the ABR principal components latencies were confronted.


Subject(s)
Evoked Potentials, Auditory, Brain Stem , Head , Sex Characteristics , Adult , Cephalometry , Evoked Potentials, Auditory, Brain Stem/physiology , Female , Humans , Male , Reference Values
2.
Pharmatherapeutica ; 5(3): 170-6, 1988.
Article in English | MEDLINE | ID: mdl-3283777

ABSTRACT

Seventy-six patients with labyrinthine diseases of vascular origin were treated in a 6-week double-blind comparative study with either 400 mg pentoxifylline ('Trental') or 75 mg cinnarizine 3-times daily. Clinical evaluations, supported by audiological tests and vectornystagmography, were carried out before and after treatment. Statistical analysis of the results showed pentoxifylline to be globally superior to cinnarizine and especially to have a more intense antivertiginous effect. No significant differences were observed between the two drugs in respect of tinnitus and hearing loss therapy. Side-effects were occasional, mild and well tolerated in the pentoxifylline group, and more pronounced and frequent with cinnarizine.


Subject(s)
Cinnarizine/therapeutic use , Labyrinth Diseases/drug therapy , Pentoxifylline/therapeutic use , Theobromine/analogs & derivatives , Aged , Audiometry , Cinnarizine/adverse effects , Clinical Trials as Topic , Double-Blind Method , Electronystagmography , Female , Humans , Labyrinth Diseases/physiopathology , Male , Middle Aged , Pentoxifylline/adverse effects , Random Allocation
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