[The importance of the plasma proteins of the blood in maintaining the relative constancy of its hydrolytic properties]. / Znachenie belkov plazmy krovi v obespechenii otnositel'nogo postoianstva ee gidroliticheskikh svoistv.

Effects of hypervolemia, dehydration, activation and inhibition of urine-formation, i. v. administration of amylase and pepsinogen, experimental acute pancreatitis upon amylolytic activity of blood plasma, contents of pepsinogen in it, amylase and pepsinogen within the blood plasma protein factions, and excretion of enzymes with the urine, were studied in dogs. The data obtained suggest an important role of interconnection between amylase and pepsinogen with the plasma proteins in their renal and extrarenal excretion from the organism and in maintenance of a relative constancy of the contents and activity of enzymes in the blood. The affinity of the plasma proteins to their stains can indirectly characterise the transport capacity of the proteins in respect to amylase and pepsinogen.

[The role of the proteins of the blood plasma in the homeostasis of its amylase and pepsinogen]. / Rol' belkov plazmy krovi v gomeostaze ee amilazy i pepsinogena.

Hypervolemia and stimulation of diuresis in dogs was found to decrease the amylolytic activity of the blood plasma and pepsinogen concentration. The number of enzymes bound with blood plasma albumins decreases in hyper-fermentation. The changing connexion of the plasma albumins with the enzymes entails a renal (as well as extrarenal) extraction of the enzymes from the organism and maintenance of their relatively constant concentration and activity in the blood.