[Disorders of glucose tolerance and ischemic heart disease]. / Narushenie tolerantnosti k gliukoze i ishemicheskaia bolezn' serdtsa.

The incidence of impaired glucose tolerance, the relation of blood glucose levels to the prevalence of risk factors for coronary heart disease (CHD) and to myocardial infarction morbidity and mortality were studied over 15 years among males aged 45-59 years, excluding patients with diabetes mellitus. The data analysis was made in quintils of glucose levels. Impaired glucose tolerance was detected in 20.6% of the males. In the fifth versus the first quintil, there was an increase in the prevalence of systolic and diastolic arterial hypertension (p less than 0.001), obesity (p less than 0.001), low physical activity and hypercholesterolemia (p less than 0.05). As compared with the first, the fifth quintil showed higher total mortality rates and higher myocardial infarction morbidity and cardiovascular disease and CHD morbidity rates. But for age, and major risk factors, the risk for CHD, total and cardiovascular mortality increase at low and high blood glucose concentrations.

[Comparative evaluation of mortality and incidence of ischemic heart disease among participants and non-participants in a population study]. / Sravnitel'naia otsenka smertnosti i zabolevaemosti ishemicheskoi bolezn'iu serdtsa sredi uchastnikov i neuchastnikov populiatsionnogo issledovaniia.

The groups of participants (5946 males) and nonparticipants (2626 males) in a population study, carried out in Kaunas, were compared on the basis of a 4.5-year follow-up, making use of the acute myocardial infarction register and the mortality register. The total mortality rate, as well as the rates of mortality due to cardiovascular diseases, traumas and accidents were higher in nonparticipants, as compared to the participants. The detectability of recent coronary disease was also higher among those who refused to participate in the study: 5.46 vs. 4.41, respectively, per 1000 people per year (p less than 0.05). It is demonstrated that particular attention must be paid to individuals avoiding preventive screening programs.

[Intermittent claudication and risk factors among men 40 to 59 years of age based on the data of a prospective population study]. / Peremezhaiushchaiasia khromota i faktory riska sredi muzhchin 40--59-letnego vozrasta po dannym prospektivnogo populiatsionnogo issledovaniia.

A study was made of the prevalence of intermittent claudication (IC) and risk factors among men aged 40 to 59 years and of the acute myocardial infarction lethality and incidence during ten years of the follow up. Using standard techniques a representative group of 6117 men were examined. The prevalence of IC amounted to 0.89% in the group under study (standardized according to age). Analysis of the relationship between the prevalence of IC and risk factors has demonstrated the presence of the significant correlation only among men with hypercholesterolemia and tobacco smokers. In men who suffered myocardial infarction, the rate of IC was higher than in men with angina pectoris of effort, painless coronary disease or without coronary disease. Analysis of the acute myocardial infarction lethality and incidence has shown that they are significantly higher among men with IC than in those without this pathology.