ABSTRACT
Four new polyketides, (R)-4-hydroxyeleutherin, eleuthone, eleutherinol-8-O-ß-D-glucoside and isoeleuthoside C (dihydroisoeleutherin-5-O-ß-D-gentiobioside) were isolated from the bulbs of Eleutherine bulbosa, to join eleutherin, isoeleutherin, eleutherinol, eleutherol, eleuthoside B (eleutherol-4-O-ß-D-gentiobioside), eleuthoside C (dihydroeleutherin-5-O-ß-D-gentiobioside), hongconin (4-oxodihydroisoeleutherin) and elecanacin, which have already been isolated from the same plant. The structures of the new polyketides, based on oxydated cyclic systems, have been elucidated by chemical and spectroscopic methods.
Subject(s)
Iridaceae/chemistry , Macrolides/isolation & purification , Macrolides/chemistry , Molecular Structure , Plant Roots/chemistry , Plants, Medicinal/chemistryABSTRACT
From the root bark of Jasminum abyssinicum (Oleaceae) collected in Congo was isolated tree oligomeric secoiridoid glucosides named craigosides A-C. The three compounds are esters of a cyclopentanoid monoterpene with an iridane skeleton, esterified with three, two and two, respectively, units of oleoside 11-methyl ester. The structures were elucidated by spectroscopic methods and chemical correlations.
