Use of Telehealth for Domiciliary Follow-up After Hematopoietic Cell Transplantation During the COVID-19 Pandemic: Prospective Pilot Study.

BACKGROUND: Patients who have recently received a hematopoietic cell transplant (HCT) are at higher risk of acute complications in the first weeks after discharge, especially during the COVID-19 pandemic. OBJECTIVE: The aim of this study was to test the use of a telehealth platform for the follow-up of HCT patients during the first two weeks after discharge. METHODS: In total, 21 patients who received autologous or allogeneic HCT for hematological malignancies were screened from April 30, 2020, to July 15, 2020. The telehealth platform assisted in the daily collection of vital signs as well as physical and psychological symptoms for two weeks after hospital discharge. The required medical devices (oximeter and blood pressure monitor) were given to patients and a dedicated smartphone app was developed to collect this data. The data were reviewed daily through web-based software by a hematologist specializing in HCT. RESULTS: Only 12 of 21 patients were able to join and complete the study. Technological barriers were the most frequent limiting factor in this study. Among the 12 patients who completed the study, adherence to data reporting was high. The patients' experience of using such a system was considered good. In two cases, the system enabled the early recognition of acute complications. CONCLUSIONS: This pilot study showed that telehealth systems can be applied in the early posttransplant setting, with evident advantages for physicians and patients for both medical and psychological aspects. Technological issues still represent a challenge for the applicability of such a system, especially for older adult patients. Easier-to-use technologies could help to expand the use of telehealth systems in this setting in the future.

Linfoma difuso de células grandes B asociado a metotrexato en un paciente afecto de una leucemia linfoblástica aguda / Diffuse large B cell lymphoma associated with methotrexate in a patient with acute lymphoblastic leukemia

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Development of a novel mindfulness and cognitive behavioral intervention for stress-eating: a comparative pilot study.

Stress-related eating is increasingly cited as a difficulty in managing healthy eating behaviors and weight. However few interventions have been designed to specifically target stress-related eating. In addition, the optimal target of such an intervention is unclear, as the target might be conceptualized as overall stress reduction or changing emotional eating-related thoughts and behaviors. This pilot study compared the effects of three interventions targeting those components individually and in combination on stress-related eating, perceived stress, and weight loss to determine whether the two intervention components are effective alone or are more effective when combined. Fifty-three overweight participants (98% female) who reported elevated levels of stress and stress-eating and were at risk for obesity were randomly assigned to one of three six-week interventions: a modified mindfulness-based stress reduction (MBSR) intervention, a cognitive behavioral stress-eating intervention (SEI), and a combined intervention that included all MBSR and SEI components. All three interventions significantly reduced perceived stress and stress-eating, but the combination intervention resulted in greater reductions and also produced a moderate effect on short term weight loss. Benefits persisted at six week follow-up.The pattern of results preliminarily suggests that the combination intervention (MBSR+SEI) may yield promise in the treatment of stress-related eating.

Factor structure and predictive utility of the Binge Eating Scale in bariatric surgery candidates.

BACKGROUND: Screening for binge eating before bariatric surgery is a component of the recommended clinical practice for bariatric surgery candidates. The Binge Eating Scale (BES) is 1 of the most commonly used self-report measures of eating behaviors in preoperative evaluations; however, the factor structure of this measure has not been evaluated in the bariatric population. The aims of the present study were to report the mean, standard deviation, and reliability of the BES for patients seeking bariatric surgery; to evaluate the 2-factor structure of the BES using confirmatory factor analysis; and to investigate the association between the BES and its factors with surgical weight loss. The setting was an academic medical center. METHODS: A total of 530 patients completed the BES as a component of their psychological evaluation before undergoing Roux-en-Y gastric bypass surgery. RESULTS: Approximately one third of patients reported at least mild to moderate binge eating, with 9% of patients reporting severe binge eating on the BES. The BES demonstrated good internal consistency. The results of the confirmatory factor analysis indicated that a 2-factor structure, consisting of feelings/cognitions related to binge eating and behavioral manifestations of binge eating, was the best fit to the data. Nonsignificant correlations were found between the BES and its 2 factors with short-term postoperative weight loss. CONCLUSION: The BES measures 2 aspects of binge eating in bariatric surgery candidates, feelings/cognitions and behavioral manifestations of binge eating. Consideration of these factors in patients presenting for bariatric surgery could allow for a more detailed understanding of binge eating in this population.

Confirmatory factor analysis of the Beck Depression Inventory-II in bariatric surgery candidates.

Screening for depression is an integral part of psychological evaluations conducted prior to bariatric surgery. The Beck Depression Inventory-II (BDI-II) is the most commonly used measure of depression in these treatment evaluations. The reliability and validity of the BDI-II has not yet been evaluated within bariatric surgery-seeking samples, evidencing a significant gap in the present literature. The purpose of the present study is to evaluate the structural validity of the BDI-II and to examine the reliability and convergent and criterion validity of this instrument within a bariatric surgery-seeking sample. The study population consisted of 505 ethnically diverse bariatric surgery candidates presenting for presurgical psychological evaluations in a midwestern urban academic medical center. Confirmatory factor analytic results indicated that a 3-factor model consisting of affective, cognitive, and somatic factors was the best fitting model of depression within this sample. Internal consistency reliability was satisfactory for each subscale, ranging from .72 to .82. Moderate to large correlations were observed between each BDI-II subscale and a measure of depression previously validated with bariatric surgery candidates indicating adequate convergent validity. On the basis of clinical interview, 14% of the sample was diagnosed with current major depression. Significant mean differences were observed between depressed and nondepressed patients with respect to each BDI-II subscale score, demonstrating criterion-related validity. The BDI-II is a reliable and valid measure of depression for bariatric surgery candidates. Understanding the factor structure of the BDI-II can be useful for planning potential presurgical psychological interventions.

The BRIGHTEN program: implementation and evaluation of a program to bridge resources of an interdisciplinary geriatric health team via electronic networking.

PURPOSE: To demonstrate the feasibility of the BRIGHTEN Program (Bridging Resources of an Interdisciplinary Geriatric Health Team via Electronic Networking), an interdisciplinary team intervention for assessing and treating older adults for depression in outpatient primary and specialty medical clinics. The BRIGHTEN team collaborates "virtually" to review patient assessment results, develop a treatment plan, and refer to appropriate team members for follow-up care. DESIGN AND METHODS: Older adults in 9 academic medical center clinics and 2 community-based clinics completed screening forms for symptoms of depression and anxiety. Those with positive screens engaged in comprehensive assessment with the BRIGHTEN Program Coordinator; the BRIGHTEN virtual team provided treatment recommendations based on the results of assessment. A collaborative treatment plan was developed with each participant, who was then connected to appropriate services. RESULTS: Two thousand four hundred twenty-two older adults were screened in participating clinics over a 40-month period. Eight hundred fifty-nine older adults screened positive, and 150 elected to enroll in BRIGHTEN. From baseline to 6 months, significant improvements were found in depression symptoms (Geriatric Depression Scale, p < .01) and general mental health (SF-12 Mental Component, p < .01). IMPLICATIONS: The BRIGHTEN Program demonstrated that an interdisciplinary virtual team linked with outpatient medical clinics can be an effective, nonthreatening, and seamless approach to enable older adults to access treatment for depression.

Revisiting the revised master questionnaire for the psychological evaluation of bariatric surgery candidates.

BACKGROUND: This study aims to evaluate the Revised Master Questionnaire (MQR), a measure of cognitive and behavioral difficulties related to weight management, for use in bariatric surgery evaluations. The MQR's five domains include stimulus control, hopelessness, motivation, physical attribution, and energy balance knowledge, all of which are relevant to bariatric surgery evaluation. METHODS: Participants were 790 bariatric surgery candidates presenting for psychological evaluation in an urban medical center. Internal consistency reliability analyses were performed on the overall scale and subscales. Confirmatory factor analysis using principal components analysis was performed and the results compared with the original behavioral weight loss sample. Convergent validity with the Beck Depression Inventory (BDI) and Binge Eating Scale (BES) were evaluated. Differences in normative data for subgroups of the bariatric sample (by obesity category and by surgery type) were also evaluated. RESULTS: Alpha coefficients and mean inter-item correlations were largely acceptable and similar to the original behavioral weight loss sample. Factor analyses supported the consistency of the underlying factor structure. Convergent validity between the BDI and BES and relevant subscales was obtained. Overall, bariatric surgery candidates had significantly more adaptive scores than behavioral weight loss patients on three of the five scales; however, scores on physical attribution and energy balance knowledge were significantly lower. Candidates for gastric banding surgery had significantly more adaptive scores on all five subscales than candidates for gastric bypass surgery. CONCLUSIONS: The MQR evaluates important but under-assessed weight control-related constructs and has acceptable psychometric properties. Based on these findings, it is recommended for use as a component of the psychological evaluation for bariatric surgery.

An exploratory study of inducing positive expectancies for psychotherapy.

OBJECTIVES: The goal of this study was to determine whether explicit presentation of outcome data about the effectiveness of psychotherapy among older adults increased positive expectancy for treatment. METHOD: The study included an ethically diverse sample of 50 adults over age 60 who screened positive for depression and agreed to participate in the BRIGHTEN Program, an interdisciplinary geriatric mental health program. Prior to treatment initiation, we presented participants with outcome data about psychotherapy, asked participants to rate and respond to the data, and asked participants about prior experience with mental health treatment. These data were collected via semi-structured interviews. RESULTS: Higher importance ratings for the outcome data were significantly associated with starting psychotherapy (r = 0.30, p = 0.04). Depression severity predicted importance assigned to the outcome data (ß = 0.36, p = 0.03), more severely depressed participants rated the outcome data as more important. Qualitative analyses indicated that the presentation of outcome data increased hopefulness for successful treatment. In a hierarchical regression analysis, hopefulness in the data predicted data importance ratings, above and beyond the influence of depression severity (ß = 0.50, p < 0.01). CONCLUSION: Our results suggest that information about the effectiveness of psychotherapy was important to participants and was associated with starting psychotherapy. High importance ratings for the data were primarily driven by the data increasing hopefulness for successful treatment outcomes. Although this study was exploratory, it suggests that explicit presentation of the effectiveness of psychotherapy may create positive expectancies for treatment among older adults.