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Khirurgiia (Mosk) ; (11): 13-6, 2014.
Article in Russian | MEDLINE | ID: mdl-25589178

ABSTRACT

It was analyzed the treatment results of 108 patients with pancreonecrosis (PN). Gas-liquid chromatography with definition of blood concentration of volatile fatty acids (VFA) was used additionally for timely diagnostics of infected pancreonecrosis. Volatile fatty acids are toxic metabolites of microorganisms. Statistically significant threshold values of VFA were revealed. These values allow to diagnose timely early phase of PN infection and the nature of the microflora. It was defined changes of VFA depending on the severity of infectious process in pancreas and retroperitoneal fiber.


Subject(s)
Bacteria/metabolism , Chromatography, Gas/methods , Fatty Acids, Volatile , Pancreatitis, Acute Necrotizing , Retroperitoneal Space/microbiology , Adult , Bacteria/classification , Disease Management , Early Diagnosis , Fatty Acids, Volatile/analysis , Fatty Acids, Volatile/metabolism , Female , Humans , Male , Middle Aged , Pancreatitis, Acute Necrotizing/diagnosis , Pancreatitis, Acute Necrotizing/microbiology , Pancreatitis, Acute Necrotizing/physiopathology , Pancreatitis, Acute Necrotizing/therapy , Reproducibility of Results , Retrospective Studies , Russia , Severity of Illness Index
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