Disturbances in cervico-vestibulo-oculomotor interaction in patients with late stages of Parkinson disease.

Cervico-vestibulo-oculomotor interactions in patients with Parkinson disease stages III-IV and healthy subjects were studied in horizontal head movement and gaze fixation on immobile and mobile targets. Significant changes in the amplitude, head movement frequency and asymmetry, eye movement amplitude, and phase mismatch between head and eye movements were revealed in patients in comparison to the normal.