[Diagnosis and prognosis of cerebral ischemic disturbances course using a method of artificial neuronal networks]. / Diagnostika i prognozirovanie techeniia ishemicheskoi bolezni golovnogo mozga s ispol'zovaniem metoda iskusstvennykh neironnykh setei.

Based on the data of examination of 224 patients with different stages of cerebral ischemic disturbances (CID) and 84 age-matched controls, an artificial neuronal network was constructed and tried in differential diagnosis of CID stages according to the data of transcranial ultrasonic dopplerography. Diagnostic efficacy of the network was 80% for sensitivity, 100% for specificity and 82.7% for reliability. A modeling of the influence of the main risk factors for cerebral ischemia and of the reserve state of cerebral hemodynamics for establishing the stage of CID was performed.

[Efficiency of a new method for extrapleural plastic repair of the apex of the lung in disseminated destructive tuberculosis]. / Effektivnost' novogo metoda ékstraplevral'noi plastiki verkhushki legkogo pri rasprostranennom destrukruktivnom tuberkuleze.

The Thoracic Department, Yarutsk Research Institute of Tuberculosis, has developed a new method for extrapleural plastic repair of the apex of the lung in destructive tuberculosis. The essence of the method is that pneumolysis of the apex of the lung and its bringing down is made by the well-known procedure described by L. K. Bogush after thoracoplasty. To prevent its expanding, the apex of the lung is fixed by a hammock mesh prepared before surgery. For this, No. 2 polysorb thresh is used and a 10 x 14-cm mesh is woven. The cells measure 2 x 2 cm. Then the mesh is placed in disinfectant solution. Surgery was performed in 41 patients with generalized fibrocavernous, disseminated, cavernous, and infiltrative pulmonary tuberculosis, by yielding 90.3% efficiency. The developed operation may be used during a non-stabilized tuberculous process, anterior and upper lung destructions and in the presence of a giant cavity in the lung tissue. The time course of changes in the indices of external respiratory function is indicative of a more rapid and qualitative recovery of the external respiratory apparatus and of a rapid adaptation of compensatory respiratory mechanisms in the postoperative period.

[Patterns in the change of the evoked skin autonomic potential in nervous system diseases]. / Zakonomernosti izmeneniia vyzvannogo kozhnogo vegetativnogo potentsiala pri zabolevaniiakh nervnoi sistemy.

The study of sympathetic skin response (SSR) was performed both in 30 healthy volunteers either in rest or after pharmacological preparations administration (reserpine, sydnocarb, gammalone) and in 48 patients with autonomic disfunction, syringomyelia, polyneuropathy. It was determined that two processes were presented in SSR structure, exactly: the first one which included I and III phases and was bound with trophotropic functions and the second process which was presented by II phase only and reflected the activity of ergotropic functions. The latent period of SSR reflected the tonus of the sympathetic nervous system. It was established that SSR changed regularly in the nervous systems diseases studied: thus, increase or decrease of the latent period as well as of the amplitudes of SSR phases were observed in autonomic disfunction while depression or absence of SSR took place in syringomyelia or polyneuropathies. The data obtained testified the results of the other authors about possibility of SSR usage for diagnosis of both central and peripheric autonomic disturbances.

[Autonomic paroxysms: their pathogenesis, diagnosis and treatment]. / Vegetativnye paroksizmy: patogenez, diagnostika, lechenie.

In the article the rules about etiology and pathogenesis of vegetative paroxysms are stated based on careful analysis of the publications of researches as Russian, so foreign authors, and also own experimental and clinical supervision. During experimental and clinical researches the modern methods were used, enabling to estimate from positions of the system analysis different parts of pathogenesis of vegetative paroxysms, and also to offer ways of differential diagnostics of the various forms of disease. The application of some new preparations and direction of therapy of vegetative paroxysms are substantiated, and also the various circuits of treatment of the patients with distinguishing forms of given pathology are motivated.

[Cerebrovascular reactivity in the pathogenesis of ischemic brain lesions in patients of different ages]. / Tserebrovaskuliarnaia reaktivnost' v patogeneze ishemicheskikh porazhenii mozga u bol'nykh raznogo vozrasta.

Cerebrovascular indices (cerebrovascular reactivity, plethora of pulse, the degree of atherosclerotic damage of carotids) were evaluated in 445 patients with either transient disturbances of brain's circulation or ischemic stroke. The patients' age was 32-85 years. It was found that the alterations in the system of neurogenic regulation which were the consequences of some pathogenic factors' influence (infectious diseases, closed brain's trauma, latent intoxication), resulted in some cases in formation of lower level of cerebrovascular reactivity which in turn was one of the reasons of ischemic cerebral disorder development. Further influence of such factors as atherosclerosis, increase of blood coagulability, decrease of total arterial pressure may result in alterations in cerebrovascular system's stability and in development of cerebrovascular diseases at younger age.

[A clinico-instrumental evaluation of cerebral hemodynamics in patients with occlusive lesions of the carotid arteries (its diagnostic and prognostic importance)]. / Kliniko-instrumental'naia otsenka tserebral'noi gemodinamiki u bol'nykh s okkliuziruiushchimi porazheniiami sonnykh arterii (diagnosticheskoe i prognosticheskoe znachenie).

Ultrasonic dopplerography and rheoencephalography were employed to investigate cerebral circulation in patients (n-123) with carotid artery atherosclerosis having transient disturbances of cerebral circulation or ischemic apoplexy. The ischemic foci were measured and localized at computed and NMR tomography. The above complex of examinations allowed evaluation of local, regional and overall blood filling of the brain, of collateral flow as well as conclusion on the type of cerebral hemodynamics. Focal lesions seem to arise in inadequate functioning of collateral circulation, that is in patients with unstable and decompensated hemodynamics. Active collateral circulation shown by the absence of noticeable interhemispheric asymmetry proved prognostically favourable. Administration of vasoactive drugs to patients with decompensated cerebral hemodynamics may induce stealing syndrome and aggravation of neurological symptoms.