ABSTRACT
By analyzing the findings and databases on the hygienic standardization of industrial microorganisms, the authors have improved a research program for industrial strains on substantiating their safe exposure levels in workplace and ambient airs. A shortened program is proposed to investigate gram-positive bacteria and nocardioformic actinomycetes (Lactobacillus, Micrococcus, Propionibacterim, Brevibacterim, Rhodococcus), which have no negative effect. It is necessary to study gram-negative bacteria and micromycetes (Pseudomonas, Alcaligenes, Acinetobacter, Arthrobacter, Aspergillus, Penicillum, Candida), which have pronounced immunotropic and dysbiotic properties by the full program, by including the evaluation of all observed negative effects. On the basis of this group, the priority microorganisms that confer a real danger to workers' health in developing allergic diseases have been listed.
Subject(s)
Air Microbiology/standards , Bacteria/isolation & purification , Hygiene/standards , Industry , Occupational Diseases/microbiology , Occupational Exposure/adverse effects , Humans , Occupational Exposure/analysisABSTRACT
Unusual intracytoplasmatic inclusions were found in urinary bladder neurons in dogs. The plate-like inclusions were composed of thin filaments, and when viewed en face, appeared as oval or angular bodies with regular lattice work array. When viewed in a transverse section, they were of rod-like shape and were composed of longitudinal filaments and transverse bars. The inclusions were observed in all ganglia of the urinary bladders studied. Three-dimensional reconstruction of the inclusions was made, using a tilting device. By means of this reconstruction, it could be demonstrated that their ultrastructure is similar to that of Hirano bodies which occur in human neurons of the central nervous system in cases of neurodegenerative diseases. The authors suggest that unusual intraneuronal inclusions represent a peculiarity in cytoskeletal protein assembly typical of canine urinary bladder neurons.
Subject(s)
Inclusion Bodies/ultrastructure , Neurons/ultrastructure , Urinary Bladder/innervation , Animals , Dogs , Female , Male , Microscopy, Electron , Neurons/cytology , Urinary Bladder/ultrastructureABSTRACT
Central hemodynamics (CH) were studied in 43 elderly (72.4 years) patients by means of the Swan-Ganz catheter. Analysis according to three main criteria--the clinical picture and the values of volume blood flow and jamming pressure in the pulmonary artery--disclosed several hemodynamic types. The "hypovolemic" CH variant was prevalent (17), the eukinetic type of CH was encountered in 8, the "hyperkinetic" type--in 7, and the "hypokinetic" type--in 2 patients. Some parameters of the system of oxygen transport were used as additional information. Patients with limited reserves of circulation were set apart. Additional preoperative management for correcting CH disorders was recommended for them. It is concluded that the approach to the appraisal of the condition and reserves of circulation in the elderly must be more scrupulous.
