[Functional radioisotope diagnosis in myocardial infarct]. / Funktsionalna radioizotopna diagnostika pri infarkt na miokarda.

The general and regional hemodynamics was studied in 50 patients with clinical, paraclinical and electrographic data on myocardial infarction in chronic and subacute stage via quantitative radiocardiography (ECG) and via the determination of the total coronary output (TCO). A significant reduction was radiocardiographically established of the indices of cardiac output as well as of the ejection fractions of the right and left ventricles, a manifestation of disturbed contractility of myocardium. TCO was substantially reduced (49.42%) from the normal values), an evidence of profoundly disturbed perfusion of the myocardium in the patients examined.

[201T1 study of regional myocardial perfusion using a gamma counter and the EC1020 computer]. / Izsledvane na regionarnata miokardna perfuziia s 201T1 na gama-kamera i EIM EC1020.

Myocardial perfusion was followed up after 500-1000 muCi 201TI-chloride injection at a gamma camera Pho-Gamma HP, Nuclar, Chicago with 4060 channel analyser and the images, according to the programmes of the authors, were processed with a computer type EC 1020. Some of the patients were examined by removing the detector, aiming at magnifying of the image and enhancing the differentiation ability under I cm. In some borderline cases, the patients were examined under physical loading and at rest for the differentiation of the normal from the disperfusion myocardial zones. Ninety patients were examined with myocardial infarction, obs. myocardial infarction, stenocardia and left bundle branch block. New additional data were obtained, in all the patients as: infarction zones, hypoperfusion foci, mosaic image of myocardium, vizualization of microinfarction, etc. The processing of the images of the regional myocardial perfusion with 201TI from gamma camera by computer, is a new, considerably higher stage of radioisotope diagnostics.

[Radioisotopic functional diagnosis in uncomplicated hypertension]. / Funktsionalna radioizotopna diagnostika pri neuslozhnenata khipertonichna bolest.

General hemodynamics of 70 patients with hypertonic disease was determined as well as the regional hemodynamics in 22 of them via radio-isotope methods, quantitative radiocardiography (QRCG) and determination of the total coronary output (TCO). Statistically significant decrease of circulating blood volume was radiocardiographically determined as well as increase of stroke volume and ventricular volumes and the indices of post-loading--general peripheral vascular resistance, index of aortic rigidity. The total coronary output is increased in patients with and without manifestations of left ventricular hypertrophy resulting from increased diastolic perfusion pressure.