ABSTRACT
Glycerol, alpha-carotene, and other yet unidentified compounds have been found in the ethanol extract from winter caterpillars of the black-veined white (Aporia crataegi L.). We have shown that the ethanol extract has a cryoprotective effect on human peripheral blood lymphocytes, and this activity is approximately three times higher than that of glycerol (particularly, in the case of repeated freezing), which is one of the best cryoprotectors.
Subject(s)
Butterflies/chemistry , Cryoprotective Agents/pharmacology , Lymphocytes/drug effects , Tissue Extracts/pharmacology , Animals , Biogenic Amines/isolation & purification , Biogenic Amines/pharmacology , Blood Preservation , Carotenoids/isolation & purification , Carotenoids/pharmacology , Cell Survival/drug effects , Cell Survival/physiology , Crataegus , Cryopreservation , Cryoprotective Agents/isolation & purification , Ethanol/chemistry , Freezing , Glycerol/isolation & purification , Glycerol/pharmacology , Humans , Lymphocytes/physiology , Seasons , Tissue Extracts/isolation & purificationABSTRACT
The intestinal form of salmonellosis caused by S. typhimurium and the host immunity were studied in 108 infants. 60 infants were treated with ampicillin and the other 48 infants with tobramycin. The recovery period in patients treated with tobramycin was 8 days less as compared to the patients treated with ampicillin After discontinuation of the tobramycin use the pathogen was not detected in the repeated platings. Bactericidal function of neutrophils in these patients returned to normal within 15 days after the beginning of the treatment. Tobramycin was shown to be a highly active antibiotic in the treatment of salmonellosis of infants. No side effects were observed.
Subject(s)
Enterocolitis/drug therapy , Gastroenteritis/drug therapy , Salmonella Infections/drug therapy , Tobramycin/therapeutic use , Child, Preschool , Drug Resistance, Microbial , Follow-Up Studies , Humans , Infant , Infant, Newborn , Salmonella typhimurium/drug effectsSubject(s)
Disease Reservoirs , Zoonoses/epidemiology , Animals , Animals, Wild , Carrier State/epidemiology , Disease Vectors , Geography , Humans , RussiaABSTRACT
The clinical picture of acute dysentery caused mainly by Shigella sonnei was studied in 160 children: 50 children were treated with monomycin tablets and for the treatment of 110 children monomycin in the form of amorphous powder in bottles was used. The treatment was carried out in accordance with the official instructions. Coincidence of the recovery time in the both groups was registered. When the patients were treated with monomycin tablets, 5 and 15-34 per cent of the antibiotic a daily dose was excreted with the urine and excrements respectively. It was concluded that monomycin in the from of tablets was more convenient in the treatment of children.
