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Lijec Vjesn ; 121(4-5): 126-8, 1999.
Article in Croatian | MEDLINE | ID: mdl-10437356

ABSTRACT

We report the case of a 57-year-old man treated with interrupted rifampicin therapy for urinary tract tuberculosis who experienced acute renal failure, intravascular hemolysis and toxic hepatitis. This combined adverse reactions are rare. Supportive treatment with dialysis and withdrawal of rifampicin result with complete recovery. Interrupted and intermittent therapy with rifampicin should be avoided and noncompliant patients should be given alternative treatment when possible.


Subject(s)
Acute Kidney Injury/chemically induced , Antibiotics, Antitubercular/poisoning , Chemical and Drug Induced Liver Injury/etiology , Hemolysis , Rifampin/poisoning , Antibiotics, Antitubercular/therapeutic use , Humans , Male , Middle Aged , Rifampin/therapeutic use , Tuberculosis, Urogenital/drug therapy
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