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J Obstet Gynaecol Res ; 49(11): 2761-2765, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37574095

ABSTRACT

Multimodal treatment, including assisted reproductive technology, is necessary in young patients with advanced borderline ovarian tumors. However, the details of long-term follow-up cases have not been reported. In this report, a 19-year-old patient presented with a stage IIIC serous borderline tumor. The patient underwent five fertility-sparing surgeries. The tumor did not respond to any of the three lines of chemotherapy administered. Serological and radiological responses were observed following hormonal treatment with leuprorelin, followed by a fourth surgery. Before the planned fifth surgery for complete resection of both adnexa, cryopreservation of the fertilized eggs was performed. At age 36, when the disease-free interval exceeded the previous one, we proposed embryo transfer; however, she declined fertility treatment. The patient had developed rheumatoid arthritis and childbirth not a priority. The patient had lived without any evidence of disease for 7 years following the last surgery and 20 years after the initial visit.


Subject(s)
Cystadenoma, Serous , Fertility Preservation , Ovarian Neoplasms , Precancerous Conditions , Adult , Female , Humans , Young Adult , Fertility , Follow-Up Studies , Neoplasm Recurrence, Local/pathology , Neoplasm Staging , Ovarian Neoplasms/surgery , Ovarian Neoplasms/drug therapy , Ovariectomy , Precancerous Conditions/pathology , Retrospective Studies , Organ Sparing Treatments
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