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2.
Surg Obes Relat Dis ; 6(2): 181-4, 2010 Mar 04.
Article in English | MEDLINE | ID: mdl-20359670

ABSTRACT

BACKGROUND: The continuous infusion of ropivacaine is effective in controlling pain for a wide variety of surgical procedures and reducing opioid adverse effects and dependency. The present study assessed the efficacy of ropivacaine infusion using the I-Flow dual Soaker Catheter system at the surgical site for bariatric surgery recovery at the Dallas Veterans Affairs Medical Center Hospital (Dallas, TX). We hypothesized that patients receiving ropivacaine would report lower levels of morphine requirement and pain, would have shorter hospital stays, and would return to ambulating faster than patients in the control group. METHODS: A total of 45 patients undergoing Roux-en-Y gastric bypass surgery were randomized to 1 of 2 treatment groups, with a target study population of 50 patients, receiving either .2% ropivacaine (n = 24) or saline solution (n = 21). Before incision closure, the surgeon infiltrated the surrounding tissues with 30 mL of ropivacaine (.5%) or saline solution. The catheter was then placed in both the subfascial space and subcutaneously. Next, the infusion pump was connected to the Soaker Catheters to complete the system design and deliver solution to the surgical site. RESULTS: No significant differences were found in the pain scores, morphine requirement, or length of stay between the 2 groups. The ropivacaine group interval to sitting up was one half day shorter than that of patients receiving saline (P = .038). CONCLUSIONS: Patients receiving ropivacaine were found to ambulate much more quickly than did the control group patients. This could be very beneficial in reducing the complications from blood clots and improving patient recovery and overall well-being after surgery by assisting with a quicker return to activities of daily living and reducing the dependence on the nursing staff.


Subject(s)
Amides/administration & dosage , Anesthetics, Local/administration & dosage , Gastric Bypass , Pain, Postoperative/drug therapy , Catheters, Indwelling , Humans , Pain Measurement , Pain, Postoperative/prevention & control , Ropivacaine
3.
J Clin Anesth ; 19(7): 530-3, 2007 Nov.
Article in English | MEDLINE | ID: mdl-18063208

ABSTRACT

STUDY OBJECTIVE: To evaluate the effects of metoclopramide on the frequency and severity of propofol-induced movements. DESIGN: Randomized, double blind, placebo-controlled trial. SETTING: Veterans Administration Medical Center. PATIENTS: One hundred thirty-seven consenting adults scheduled to receive general anesthesia with propofol induction. INTERVENTIONS: Patients were randomized to receive either metoclopramide 10 mg intravenously (IV) or placebo (saline) 3 min before induction of general anesthesia. All patients received midazolam 1 to 2 mg IV, fentanyl 50 to 150 microg IV, and lidocaine 50 to 80 mg IV before induction of anesthesia. MEASUREMENTS: Occurrence of spontaneous movements and severity during the observation period were recorded after propofol induction by observing movement in the hands/arms and feet/legs, as well as presence of a hiccup. The dosage of anesthetic medications administered was also recorded for each patient. MAIN RESULTS: No differences were noted in the frequency and severity of spontaneous movement in the patients who had received metoclopramide and placebo. However, compared with the patients who did not move, patients who experienced movements received a significantly higher dose of propofol (P = 0.025) and a lower dose of fentanyl (P = 0.049). CONCLUSIONS: Metoclopramide does not affect the frequency of propofol-induced movements, but propofol and fentanyl doses influence the frequency of movements during propofol induction.


Subject(s)
Anesthetics, Intravenous/adverse effects , Antiemetics/therapeutic use , Metoclopramide/therapeutic use , Myoclonus/chemically induced , Myoclonus/prevention & control , Propofol/adverse effects , Aged , Anesthesia, General , Antiemetics/adverse effects , Double-Blind Method , Drug Interactions , Female , Fentanyl , Hiccup/chemically induced , Hiccup/epidemiology , Humans , Hypnotics and Sedatives , Male , Metoclopramide/adverse effects , Midazolam , Middle Aged , Sample Size
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