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Can J Ophthalmol ; 47(1): 16-20, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22333845

ABSTRACT

OBJECTIVE: To evaluate the efficacy of photodynamic therapy (PDT) for symptomatic circumscribed choroidal hemangioma (CCH). DESIGN: A retrospective case series analysis through chart review of patients with CCH treated by means of PDT. PARTICIPANTS: Thirteen patients with circumscribed choroidal hemangioma. METHODS: Through retrospective charts review, the patients' demographics, clinical features, management, and follow-up data were obtained and analyzed. Outcome measures were change in visual acuity, required sessions, and adjunctive treatments. RESULTS: Median follow-up was 26 months. Seven patients (54%) underwent only 1 session, 5 patients (38%) 2 sessions, and 1 received 5 sessions and was finally treated with external beam radiotherapy (EBRT). Visual acuity improved by at least 1 line (1-5) in 11 patients and remained stable in 2. Exudative subretinal fluid was completely resolved in 92% of the cases at the last visit. No major local side effects were found. CONCLUSIONS: PDT of CCH can effectively induce tumor regression and resolution of exudative subretinal fluid, improving, or stabilizing vision.


Subject(s)
Choroid Neoplasms/drug therapy , Hemangioma/drug therapy , Photochemotherapy , Adult , Aged , Choroid Neoplasms/pathology , Female , Follow-Up Studies , Hemangioma/pathology , Humans , Male , Middle Aged , Photosensitizing Agents/therapeutic use , Porphyrins/therapeutic use , Retrospective Studies , Tomography, Optical Coherence , Treatment Outcome , Verteporfin , Visual Acuity/physiology
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