Spermine Induces Autophagy in Plants: Possible Role of NO and Reactive Oxygen Species.

This is the first study to show that polyamine spermine, a low-molecular-weight nitrogen-containing compound, can induce autophagy in plants. This process is accompanied by an increased generation of reactive oxygen species and nitric oxide, which play a signal role and are required for triggering autophagy.

Nitric oxide level in the rat tissues increases after 30-day hypokinesia: studies by electron paramagnetic resonance (EPR) spectroscopy.

Studies by EPR spectroscopy showed that 30-day exposure of rats to augmenting hypokinesia led to a 3-fold increase in nitric oxide (NO) production in the heart and 2-fold in the liver. These results indicated that long-term hypokinesia stimulated NO synthesis.