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Phytother Res ; 18(6): 494-6, 2004 Jun.
Article in English | MEDLINE | ID: mdl-15287077

ABSTRACT

This study reports on the capacity of actinomycete strains isolated from Cuban soils to produce antifungal agents. The antimicrobial activities were determined by susceptibility disk assay methods. We isolated 563 different actinomycetes and 286 produced compounds with antifungal activity. Our screening method indicated the presence of many possible polyene macrolide antibiotics and the important antifungal activity in the soils rich in minerals.


Subject(s)
Actinobacteria , Anti-Bacterial Agents/pharmacology , Antifungal Agents/pharmacology , Phytotherapy , Soil Microbiology , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Antifungal Agents/administration & dosage , Antifungal Agents/therapeutic use , Cuba , Humans , Microbial Sensitivity Tests , Micromonospora/drug effects , Streptomyces/drug effects
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